摘要
目的探讨前列腺动脉栓塞术(PAE)、经尿道前列腺电切术(TURP)及保守治疗良性前列腺增生(benign prostatic hyperplasia,BPH)的近远期疗效。方法回顾性分析2012年4月—2014年4月收治的94例BPH的临床资料,按治疗方式分为PAE组31例、TURP组39例和保守治疗组24例。观察治疗前和治疗后3、6、12、24个月最大尿流率(Qmax)、残余尿量(RUV)、夜尿次数、前列腺体积,评估国际前列腺症状评分(IPSS)和生活质量评分(QOL),记录PAE组和TURP组术后及随访期间并发症,记录3组术后阴茎勃起功能障碍(ED)和逆行射精(RE)发生率。结果PAE组、TURP组治疗后3、6、12、24个月Qmax高于保守治疗组,RUV、夜尿次数、前列腺体积、IPSS、QOL评分低于保守治疗组(P<0.05);PAE组治疗后3个月Qmax、RUV、夜尿次数、IPSS和QOL评分改善情况较TURP组差,前列腺体积小于TURP组(P<0.05);PAE组术后并发症发生率低于TURP组,随访期间并发症发生率高于TURP组(P<0.05)。3组ED、RE发生率比较差异无统计学意义(P>0.05)。结论 PAE、TURP治疗BPH可显著改善临床症状,但TURP术后3个月症状缓解情况优于PAE。
Objective To investigate short-term and long-term effects of prostatic arterial embolization（ PAE）,transurethral resection of prostate（ TURP） and conservative treatment in treatment of benign prostatic hyperplasia（ BPH）. Methods Clinical data of 94 patients with BPH admitted between April 2012 and April 2014 was retrospectively analyzed,and the patients were divided into PAE（ n = 31）,TURP（ n = 39） and conservative treatment groups（ n =24） according to different treatment methods. In two groups,maximum urinary flow rate（ Qmax）,residual urine volume（ RUV）,times of nocturnal enuresis and prostate volume were detected before treatment and in the 3rd,6th,12 thand 24th months after treatment; international prostate symptom score（ IPSS） and quality of life（ QOL） were evaluated. Postoperative complications during follow-up in PAE and TURP groups were recorded,and incidence rates of postoperative penile erectile dysfunction（ ED） and retrograde ejaculation（ RE） in three groups were also recorded. Results Qmax values in the 3rd,6th,12 thand 24thmonths after treatment were higher,while values of RUV,times of nocturnal enuresis,prostate volume,IPSS and QOL scores were lower in PAE and TURP groups than those in conservative treatment group（ P〈0. 05）. Improvement conditions of Qmax,RUV,times of nocturnal enuresis,IPSS and QOL scores in the 3rdmonth after treatment in PAE group were more significant than those in TURP group,and prostate volume in PAE group was less than that in TURP group（ P〈0. 05）. In PAE group,incidence rate of postoperative complications was lower,while incidence rate of complications during follow-up was higher than those in TURP group（ P〈0. 05）. There were no significant differences in incidence rates of ED and RE among three groups（ P〉0. 05）. Conclusion Both AE and TURP can significantly improve clinical symptoms in treatment of BPH,but the symptomatic relief in postoperative 3 months by TURP is better than that by PAE.
出处
《解放军医药杂志》
CAS
2016年第12期91-95,共5页
Medical & Pharmaceutical Journal of Chinese People’s Liberation Army
基金
陕西省科学技术研究发展计划项目(2012K16-09-014)
关键词
良性前列腺增生
动脉栓塞术
药物
最大尿流量
远期疗效
Benign prostatic hyperplasia
Arterial embolization
Drug
Maximum urinary flow
Long-term effect
