摘要
目的：分析代谢综合征和肾癌恶性程度的相关性。方法：收集2013年1月-2016年1月期间我院收治的668例肾癌手术治疗患者的一般资料,根据有无代谢综合征分为单纯性肾癌组和肾癌合并代谢综合征组。统计分析两组间肾癌Fuhrman分级的差异。结果：本研究共纳入668例肾细胞癌患者,平均年龄为（62.7±9.0）岁,男性451例,女性217例,病理类型为透明细胞癌588例,非透明细胞癌80例。单纯肾癌组包含552例患者,平均年龄（62.5±9.0）岁,男性375例,女性177例,病理类型为透明细胞癌486例,非透明细胞癌66例。Fuhrman分级Ⅰ、Ⅱ级399例,Fuhrman分级Ⅲ、Ⅳ级153例;肾癌合并代谢综合征组包括116例患者,平均年龄（63.7±8.9）岁,男性76例,女性40例,病理类型为透明细胞癌102例,非透明细胞癌14例。Fuhrman分级Ⅰ、Ⅱ级71例,Fuhrman分级Ⅲ、Ⅳ级45例。肾癌合并代谢综合征组患者的Fuhrman分级明显高于单纯肾癌组,且存在统计学意义（P=0.018）。结论：肾癌伴有代谢综合征预示了更高的恶性程度。
Objective：To analyze the correlation between metabolic syndrome and malignant degree of renal cell carcinoma.Method：The general data of 668 patients with renal cell carcinoma treated in our hospital from January 2013 to January 2016 were collected and divided into two groups according to whether is accompanied by metabolic syndrome.The statistical analysis was made in the different Fuhrman grades between two groups.Result：The study included 668 patients with renal cell carcinoma,with an average age of（62.7±9.0）years old.There were 451 males and 217 females.Pathological type showed clear cell carcinoma in 588 cases,non-clear cell carcinoma in 80 cases.The non-metabolic syndrome group included 552 patients,whose mean age was（62.5±9.0）years old.There were 375 males and 177 females.Pathological type showed clear cell carcinoma in 486 cases and non-clear cell carcinoma in 66 cases.Fuhrman grade Ⅰ,Ⅱ were found in 399 cases and grade Ⅲ,Ⅳ were found in 153 cases.The metabolic syndrome group included 116 patients whose mean age was（63.7±8.9）years old.There were 76 males and 40 females.Pathological type showed clear cell carcinoma in 102 cases and non-clear cell carcinoma in 14 cases.Fuhrman gradeⅠ,Ⅱ were found in 71 cases and gradeⅢ,Ⅳ were found in 45 cases.Patients with metabolic syndrome had significantly higher Fuhrman grade with a statistical significance（P=0.018）.Conclusion：Renal cell carcinoma associated with metabolic syndrome indicates a higher degree of malignancy.
作者
吕建敏
李霖
刘溪
潘秀舞
黄海
杨启维
王林辉
崔心刚
徐丹枫
LV Jianmin LI Lin LIU Xi PAN Xiuwu HUANG Hai YANG Qiwei WANG Linhui CUI Xin＇gang XU Danfeng(Department of Urology, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China Department of Urology, Third Affiliated Hospital of Second Military Medical University)
出处
《临床泌尿外科杂志》
2016年第12期1088-1091,共4页
Journal of Clinical Urology
