摘要
帕金森病(PD)是一种常见的神经系统变性疾病。PD患者除表现为典型的运动症状外,还具有一些非运动症状,如认知、情绪和睡眠等方面的改变。大部分PD患者在病程中会出现自主神经功能障碍,如便秘、排尿异常、性功能障碍、多汗、直立性低血压等。直立性低血压在PD患者中有较高的发生率,影响患者生活质量,文中就PD患者直立性低血压的诊断、病理生理机制及相关研究做一综述。
Parkinson＇s disease（PD） is a common nervous system degenerative disease. Apart from motor symptoms, patients with PD also have some non-motor symptoms, such as anxiety, depression, sleep disorders, cognitive disorders, etc. In the course of Parkinson＇s disease, most of the patients had autonomic dysfunction, such as constipation, abnormal urination, sexual dysfunction, sweating, orthostatic hypotension（OH）. The prevalence of OH was high in Parkinson＇s disease, and it affected the life of patients seriously. The diagnosis, pathophysiological mechanisms and the related research were discussed.
作者
白洁
周明珠
刘振国
BAI Jie ZHOU Ming-zhu LIU Zhen-guo(Department of Neurology, Xinhua Hospital, the Medical College of Shanghai, Jiaotong University, Shanghai 200092, Chin)
出处
《中国临床神经科学》
2016年第6期705-707,712,共4页
Chinese Journal of Clinical Neurosciences
关键词
帕金森病
直立性低血压
病理生理机制
诊断
Parkinson＇s disease
orthostatic hypotension
pathophysiological mechanisms
diagnosis
