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非小细胞肺癌淋巴结转移规律的临床病理学特征分析 被引量:7

Clinicopathological features of lymph node metastasis rules of non-small cell lung cancer
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摘要 目的 探讨非小细胞肺癌(NSCLC)患者淋巴结转移规律的临床病理学特征。方法对80例NSCLC患者施行患侧肺手术切除并行广泛肺门、肺叶间及纵隔淋巴结清扫术,共清扫602组淋巴结,分析NSCLC的淋巴结转移规律与临床病理特征的关系,并结合T分期、病理学类型、分化程度及原发部位进行统计分析。结果 在共清扫的602组淋巴结中,单纯N1淋巴结转移率为18.8%,N2淋巴结转移率30.4%;原发性NSCLCT分期T1、T2、T3、T4间淋巴结转移率差异有统计学意义(χ^2=50.702,P=0.000);跳跃式转移占N2转移的31.8%。结论 NSCLC的淋巴结转移与T分期有关,具有较多的跳跃性纵隔淋巴结转移发生,肿瘤部位及肺癌的病理学类型与淋巴结的转移无明显关系。 Objective To explore the clinicopathological features of the lymph node metastasis rules of non?small cell lung cancer ( NSCLC).Methods Eighty cases of lung cancer patients underwent surgical resection and lymph node dissection of extensive hilar,leaves room and mediastinum.A total of 602 groups of lymph nodes were removed. The lymph node metastasis rules of NSCLC and their relations with clinicopathological features were analyzed.T stage,pathologic type,differentiation degree and the primary site were statistically analyzed.Results Among the 602 groups of lymph nodes,the metastatic rates of N1 and N2 ( including N1+N2 ) nodes were 18. 8% and 30. 4%. There were significant differences in lymph node metastasis among primary lung cancer T stage T1, T2, T3 and T4 ( χ^2 =50. 702, P =0. 000 ) . Saltatory metastatic nodes accounted for 31.8% of N2 metastatic nodes.Conclusions Lymph node metastasis is related with T staging of NSCLC, with more jumping mediastinal lymph node metastasis. There are no significant relationships between tumor location,pathological types or type of lymph node metastasis.
出处 《中华诊断学电子杂志》 2016年第4期249-252,共4页 Chinese Journal of Diagnostics(Electronic Edition)
关键词 非小细胞肺 淋巴结转移 淋巴结切除术 疾病特征 Carcinoma,non-small-cell lung Lymph node excision Lymphadenectomy Disease features
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