摘要
目的探讨比较急性脑缺血在动态磁敏感对比(DSC)MRI与磁敏感加权成像(SWI)上的表现,为临床治疗提供科学有效的影像参考。方法选取经影像及临床已经确诊的且发病时间为3d内急性脑缺血患者作为观察对象,共44例。对患者予以常规MRI、DSC及SWI检查,观察影像表现。依据DSC表现具体分成正常灌注、灌注不足、过度及延迟灌注共四种;同时依据SWI影像情况分成静脉减少或者增多及正常三种。应用Mann-Whitney法对DSC与SWI两种技术结果进行一致性检验分析,在SWI所示病变部位及其对侧正常半球镜像区选择三个兴趣区域,并测量信号强度。结果在DSC上表现灌注不足者35例,其中31例在SWI上表现出病灶静脉减少或者已经消失,其余13例患者,在DSC上表现为灌注不足者4例,过度灌注6例,延迟灌注3例,而在SWI上显示正常。一致性分析显示两种技术间无显著统计学差异(P>0.05),信号强度比值比较亦无统计学差异(P>0.05)。结论 SWI与DSC比较,能够显示脑血流动力学状态,能够反映出再灌注损伤情况,与常规MRI结合,可为治疗与预后提供更有价值的参考依据。
Objective To explore acute cerebral ischemia in dynamic susceptibility contrast（DSC） MRI performance and susceptibility weighted imaging（SWI） on scientific and effective image reference for clinical treatment. Methods To choose have been confirmed and the onset time of acute cerebral ischemia in patients with 3D as the object of observation, a total of 44 cases. For patients treated with routine MRI, DSC and SWI examination, imaging observation. Based on the DSC specific into normal perfusion, hypoperfusion, excessive and delayed perfusion in a total of four, at the same time on the basis of the SWI image into vein reduced or increased and normal. Using Mann Whitney method of differential scanning calorimetry（DSC） and SWI two techniques results consistency test analysis, in the SWI shown in lesion and in the contralateral normal brain image area in three regions of interest, and measure the signal strength. Results DSC performance hypoperfusion in 35 cases, including 31 cases showed lesions on SWI vein reduced or have disappeared, and the remaining 13 patients, showed hypoperfusion in 4 cases in the DSC, hyperperfusion six cases, three cases of delayed perfusion, and the display properly on SWI. Consistency between the two technology analysis shows no significant difference（P〉0.05）, and there was no signal intensity ratio statistically significant difference（P〉0.05）. Conclusion SWI and DSC comparison, can show cerebral hemodynamic status, it can reflect reperfusion injury, combined with conventional MRI, can provide valuable reference for the treatment and prognosis.
出处
《中国CT和MRI杂志》
2017年第1期23-25,29,共4页
Chinese Journal of CT and MRI
基金
湖北省教育厅科学技术研究项目(D20112103)
关键词
急性脑缺血
动态磁敏感对比
磁敏感加权成像
Acute Cerebral Ischemia
Dynamic Susceptibility Contrast
Susceptibility Weighted Imaging
Reperfusion Injury
