摘要
目的探讨超声检查对自身免疫性甲状腺炎(AIT)患者甲状腺功能的判断价值。方法收集2011年6月至2016年6月在眉山市人民医院内分泌科门诊和(或)住院诊断的AIT患者102例的临床资料(AIT组),根据甲状腺功能的血清学检查结果,将其分为甲状腺功能正常组(正常组,20例)、甲状腺功能亢进组(甲亢组,16例)和甲状腺功能减退组(甲减组,66例)。同时选取40例同期甲状腺自身抗体阴性、血清学甲状腺功能检查正常人群作为对照组。应用高频超声观察各组研究对象不同功能状态下AIT的超声特征,测量各组甲状腺长、宽、厚径及峡部厚径与甲状腺上动脉(STA)内径及血流动力学参数,包括收缩期峰值流速(PSV)、阻力指数(RI)和心率(HR)。结果各分组研究对象甲状腺各径线值及体积均大于对照组,差异均有统计学意义(P<0.01);AIT患者低回声检出率[94.12%(96/102)]高于对照组(0),差异有统计学意义(P<0.05);甲减组低回声分级以Ⅱ、Ⅲ级为主,与正常组、甲亢组比较,差异均有统计学意义(P<0.01);甲亢组血供分级以Ⅰ、Ⅱ级为主,甲减组以Ⅱ、Ⅲ级为主,均较正常组及对照组丰富,差异均有统计学意义(P<0.05);甲亢组与甲减组的STA内径、PSV、PSVmax及RI值均大于对照组,差异均有统计学意义(P<0.01);甲减组及甲亢组PSVmax高于正常组,且甲亢组高于甲减组,差异均有统计学意义(P<0.01或0.05);甲亢组HR显著快于甲减组,差异有统计学意义(P<0.05)。结论超声检查可以在一定程度上判断AIT患者的甲状腺功能状态。
Objective To study the value of ultrasound examination for the functional judgment in the patients with au toimmune thyroiditis(AIT). Methods The clinical data of 102 cases of AIT(AIT group) diagnosed in the outpatient and/or inpatient endocrinology departments of our hospital from June 2011 to June 2016 were collected. The patients were divided into the normal thyroid function group( normal group,20 cases), hyperthyroidism group(16 cases) and hypothyroidism group(66 cases) according to the serological detection results of thyroid function. Meanwhile contemporaneous 40 individuals of thyroid au-toimmune antibody negative and normal serological detection of thyroid function were selected as the control group. The high-frequency ultrasound was used to investigate the AIT ultrasound features in each group,measure the length,width and thickness di ameters of thyroid,inner diameter of superior thyroid artery(STA) and its hemodynamic parameters including the peak systolic velocity(PSV),resistance index(RI) and heart rate(HR). Results The various radial line values and volumes in each research group were more than those in the control group,the difference was statistically significant(P〈0.01);the low echo detection rate in AIT patients[94.12%(96/102)] was higher than that in the control group(0) with statistical difference(P〈0.05);the low echo types in the hypothyroidism group were dominated by the type Ⅱ and Ⅲ,showing statistical difference compared with the normal group and hyperthyroidism group,the difference was statistically significant(P〈0.01);the blood supply types in the hyperthyroidism group were dominated by type Ⅰ and Ⅱ, which in the hypothyroidism group were dominated by the type Ⅱ and Ⅲ, all were more abundant than the normal group and control group with statistical difference(P〈0.05);the values of STA inner diameter,PSV,PSVmaxand RI in the hyperthyroidism group and hypothyroidism group were more than those in the control group,
出处
《现代医药卫生》
2016年第24期3776-3778,共3页
Journal of Modern Medicine & Health