摘要
目的 探讨妊娠前2年以上行室间隔封堵术对妊娠结局的影响。方法 采用回顾性队列研究,选取本院妇产科2012年-2015年的妊娠合并室间隔缺损患者90例,比较室间隔封堵术后对孕产妇心功能、肺动脉高压发生率、孕周及新生儿体重等的改变,并进行统计分析。结果 1、术后组心功能良好~Ⅱ级发生率较缺损组高,心功能Ⅲ~Ⅳ级较缺损组低,差异具有统计学意义（P〈0.05）。2、术后组较缺损组肺动脉高压发生率明显降低,差异具有统计学意义（P〈0.05）。3、缺损组引产、早产发生率、低体重出生儿发生率较术后组高,差异具有统计学意义（P〈0.05）。结论 室间隔缺损确诊后应尽早封堵术治疗,封堵术后两年妊娠可改善孕期的心功能状态,并提高围产儿质量。
Objective To explore VSD＇s impact on pregnancy outcome which defect occlusions over 2 years before pregnancy. Methods Using retrospective cohort study, to select 90 cases of pregnancy patients complicated with VSD from 2012 to 2015, comparing the changes after the VSD occlusion, maternal cardiac function, the incidence of pulmonary hypertension, gestational age and birth weight,then statistical analysis. Results 1. Occlusion group compared with VSD group, the incidence of good heart function - Ⅱ level were higher,Ⅲ Ⅳ level were lower, the difference was statistically significant （P〈0.05）. 2. Occlusion group compared with VSD group, the incidence of the pulmonary hypertension were lower, the difference was statistically significant （P〈0.05）. 3. Incidences of the VSD group＇s abortion, and preterm low birth weight children were higher than that of occlusion group,the difference was statistically significant （P〈0.05）. Conclusion As soon as possible the defect occlusion surgery skould be done after diagnosis of VSD. Two years after the closure, it can improve heart function during pregnancy and perinatal quality.
出处
《云南医药》
CAS
2016年第6期601-603,共3页
Medicine and Pharmacy of Yunnan
