摘要
探讨脾切除加贲门周围血管离断术后早期使用抗凝治疗的效果及安全性。方法回顾性分析2010年1月一2016年6月该院收治的53例肝硬化门静脉高压症行脾切除、贲门周围血管离断术的病例,根据术后是否早期抗凝治疗分为对照组、观察组(早期抗凝治疗)两组,统计并比较两组患者术后PVT发生率、PLT、PT、APTT、腹腔引流液量的变化。观察术后是否有出血等并发症。结果观察组患者术后门静脉血栓形成率显著低于对照组(5.6%VS 29.4%,P<0.05),腹腔引流量明显减少,且治疗期间PLT、PT、APT差异无统计系意义,未发生消化道出血和创面出血。结论脾切除加贲门周围血管离断术后早期抗凝治疗安全、有效,可减少门静脉血栓的发生。
Objective To investigate the effect and security of the early use of anticoagulant drugs after splenectomy and esophagogastric devascularization. Methods The clinical data of 53 patients with portal hypertension receiving splenectomy and esophagogastric devascularization from January 2010 to June 2016 were analyzed retrospectively. The cases were divided into control group and observational group with early use of anticoagulant drugs. The rate of postoperative thrombosis,PLT, PT, APTT, volume of intraperitoneal drainage were compared among the two groups. Observe postoperative bleeding and other complications. Results After surgery, the control group, the incidence of portal vein thrombosis was 29.4%, the observational group, the incidence was 5.6%, and the difference has significant statistical significance（P〈0.05）. Experimental group has no bleeding and other complications related to the use of anticoagulant drugs. Conclusion Early postoperative application of anticoagulant drugs after splenectomy and esophagogastric devascularization was safe and effective,could reduce portal vein thrombosis after splenectomy.
出处
《中外医疗》
2016年第33期63-65,共3页
China & Foreign Medical Treatment
关键词
门脉高压
脾切除
贲门周围血管离断术
门静脉系统血栓
抗凝
Portal hypertension
Splenectomy
Portal vein thrombosis
Esophagogastric devascularization
Anticoagulant
