摘要
目的了解许昌市健康人群百日咳、白喉、破伤风免疫水平现状及百白破疫苗(DPT)免疫成功率,为制定DPT免疫策略提供依据。方法2015年5月对许昌市健康人群分8个年龄组抽取140名健康人群,用酶联免疫吸附实验(ELISA)检测血清中百日咳、白喉、破伤风抗体水平。免疫成功率监测选择未接种过DPT基础免疫的2月龄儿童30人作为观察对象,比较DPT基础免疫前后抗体水平及免疫成功率。结果调查140人,百日咳、白喉、破伤风的抗体阳性率分别为14.29%(20/140)、76.43%(107/140)、73.57%(103/140),不同年龄组百日咳、白喉、破伤风抗体阳性率差异均有统计学意义(P<0.01);完成DPT基础免疫(3次)后儿童百日咳、白喉、破伤风免疫成功率分别为3.33%、100.00%、100.00%。结论白喉、破伤风免疫效果良好,百日咳发病风险较高。
Objective To understand the antibody levels of pertussis,diphtheria and tetanus and DPT immune success rate in the healthy population in Xuchang city,so as to provide the basis for the immunization strategy for DPT. Methods A total of 140 healthy people were divided into 8groups by age,then ELISA was used to test antibody levels of DPT.30 babies at 2months old without DPT immunization were selected as the observation objects in the immune success rate surveillance,and comparison was made on the antibody level and immune success rate of DPT before and after immunization. Results In 140 surveyed,the antibody positive rate of pertussis,diphtheria and tetanus was 14.29%（20/140）,76.43%（107/140）,and 73.57%（103/140）respectively,and the positive rates of pertussis,diphtheria and tetanus antibodies in different age groups were statistically significant（P〈0.01）;The immunization success rate of children after basic DPT immunization（3times）was 3.33%,100.00%,and 100.00%. Conclusion The immune effect of diphtheria and tetanus is good in the healthy population in Xuchang city,the risk of pertussis is higher.
出处
《预防医学论坛》
2016年第10期787-788,790,共3页
Preventive Medicine Tribune
关键词
百日咳
白喉
破伤风
抗体
Pertussis
Diphtheria
Tetanus
Antibody
Immune success rate
