摘要
目的对比分析中西医结合治疗与西医单独治疗在脑梗死后血管性痴呆患者临床中的应用。方法将2013-03—2016-03间南平市人民医院收治的84例脑梗死后血管性痴呆患者随机的分为对照组和实验组,每组各有42例患者,其中对照组患者采用单独的西医(依达拉奉注射液)治疗,实验组患者采用中西医联合疗法(依达拉奉注射液+疏血通注射液)治疗,对比分析两组患者的日常生活能力、生存质量、精神状态以及P300潜伏期。结果治疗前对照组与实验组日常生活能力分别为(32.08±9.43)分和(32.13±9.88)分,差异不显著(P>0.05),治疗后对照组日常生活能力评分下降了(5.53±1.54)分,显著的小于实验组的(8.87±1.82)分(P<0.05)。治疗前两组患者生活质量评分不存在着显著性差异(P>0.05);治疗后两组患者的生存质量都有着显著的提高,且实验组的效果更为显著。对两组患者的精神状况(MMSE)评分可知,实验组MMSE评分提高效果显著的优于对照组(P<0.05)。治疗后实验组P300潜伏期缩短了(69.14±6.83)ms,对照组P300潜伏期缩短了(42.45±7.44)ms,差异显著(P<0.05)。结论中西医结合治疗脑梗死后血管性痴呆患者的临床效果优于单独的西医治疗,能够显著的提高患者的日常生活能力和生存质量,改善患者的精神状态。
Objective To compare the clinical application of traditional Chinese medicine combined with western medicine in the treatment of vascular dementia after cerebral infarction. Methods From March,2013 to March,2016,84 patients with vascular dementia after cerebral infarction were randomly divided into control group and experimental group. Each group was consisted of 42 patients. The control group patients were treated with single western medicine（ Edaravone injection ＋ Shuxuetong injection）,and the patients in the experimental group were treated with the combination therapy of traditional Chinese medicine and western medicine（ edaravone injection ＋ shuxuetong injection）. The daily living ability,quality of life,status of two groups were compared. Results The daily living ability of the control group and the experimental group were（ 32. 08 ± 9. 43） and（ 32. 13 ± 9. 88） respectively,and the difference was not significant（ P 〉0. 05）. After treatment,the daily living ability score of the control group decreased（ 5. 53 ± 1. 54）,which was significantly lower than that of the experimental group（ 8. 87 ± 1. 82）（ P〉 0. 05）. There was no significant difference in quality of life between the two groups before treatment（ P〈 0. 05）. After treatment,the quality of life of the two groups was significantly improved,and the effect of the experimental group was more significant. The MMSE scores of the two groups were significantly higher than those of the control group（ P 0. 05）. Conclusion Integrative Chinese and western medicine treatment of cerebral infarction after vascular dementia in patients with clinical efficacy is superior to western medicine alone. It can significantly improve the patients＇ daily life and quality of life,and improve the patients＇ mental state.
作者
叶慧英
YE Hui - ying(Internal Medicine - Neurology, Fujian Nanping Peoples Hospital, Nanping, Fujian, 353000, Chin)
出处
《黑龙江医学》
2016年第11期1017-1018,共2页
Heilongjiang Medical Journal
关键词
脑梗死
血管性痴呆
日常生活能力
生存质量
精神状态
Cerebral infarction
Vascular dementia
Daily living ability
Quality of life
Mental state
