摘要
目的:探讨进行性核上性麻痹(PSP)的临床特点及影像表现。方法:回顾分析我院7例临床诊断PSP患者的临床资料和影像学表现。结果:7例患者均缓慢起病,主要临床表现为运动迟缓、姿势不稳、易跌倒及垂直性核上性眼肌麻痹,部分患者有假性球麻痹及轻度认知障碍等表现。头颅MRI表现为以中脑萎缩为主,所有患者中脑宽度<9.02 mm,中脑脑桥比值≤0.53,部分患者可见蜂鸟征及鼠耳征。结论:PSP的诊断主要依据临床表现及影像学特征,垂直性核上性眼肌麻痹具有特征性,头颅MRI中脑脑桥比值有助于PSP诊断。
Objective：To explore the clinical and imaging features of progressive supranuclear palsy （PSP）.Methods：Clinical data and imaging features were retrospectively analyzed in 7 cases of PSP.Results： Seven patients presented a gradual onset, and their clinical manifestations were characterized by bradykinesia , postural instability , easy to fall and vertical supranuclear gaze palsy .Partial patients showed pseudobulbar palsy and mild cognitive impairment .The midbrain atrophy was observed in the cranial MRI.The midbrain diameter of all cases was less than 9.02 mm, and the midbrain to pons ratio was less than or equal to 0.53.Hummingbird sign and mouse ear sign were found in some patients .Conclusion：The diagnosis of PSP is mainly based on clinical manifestations and imaging features .Vertical supranuclear gaze palsy is charateristic , and the midbrain to pons ratio of cranial MRI is useful to diagnose PSP .
出处
《现代临床医学》
2016年第6期441-442,445,共3页
Journal of Modern Clinical Medicine
关键词
进行性核上性麻痹
临床特点
核磁共振成像
progressive supranuclear palsy
clinical feature
magnetic resonance imaging
