摘要
目的探讨ICU治疗重症感染患者时的危险因素。方法回顾性分析2011年6月~2015年8月期间治疗的84例ICU治疗重症感染患者的临床资料,根据ICU治疗后患者存活情况,分为存活组(48例)和病死组(36例);对比两组患者的各项生理指标与实验室参数,进行单因素分析及多因素Logistic回归分析。结果存活组和病死组的体温、中心静脉压、APACHEⅡ评分、血小板、血尿素氮、血乳酸、血肌酐及血清钠比较,差异均有统计学意义(P〈0.05),其中存活组APACHEⅡ评分为(17.85±3.25),显著低于病死组的(30.25±7.47);血乳酸浓度(0.58±0.12)mmol/L,显著小于病死组的(3.58±1.14)mmol/L;血清钠浓度(138.6±5.27)mmol/L,显著小于病死组的(142.5±6.27)mmol/L;多因素Logistic回归分析显示,APACHEⅡ评分、血乳酸及血清钠均作为ICU治疗重症感染患者的独立危险因素。结论APACHEⅡ评分、血乳酸及血清钠均作为ICU治疗重症感染患者的独立危险因素。
Objective To investigate the risk factors of patients with ICU in the treatment of severe infection. Methods A retrospective analysis from June 2011 to August 2015 during the treatment of 84 cases of patients with ICU in the treatment of severe infection clinical data, according to the survival of patients after ICU treatment, divided into survival group (48 cases) and death group (36 cases each) ; the physiological indexes and laboratory parameters of two groups were compared by regression analysis, single factor analysis and multiple factors Logistic. Results Survival group and death group, body temperature, central venous pressure, platelet APACHE score, blood lactate, blood urea nitrogen, blood, muscle Comparison of anhydride and serum sodium, the differences were statistically significant (P 〈 0.05 ), in which the survival group APACHE Ⅱ score ( 17.85 ± 3.25 ), the mortality was significantly lower than that in (30.25±7.47) ; blood lactate concentration (0.58±0.12) mmol/L, significantly less than the death group (3.58±1.14) mmol/L; serum sodium the concentration of (138.6±5.27) mmol/L, significantly less than the death group (142.5±6.27) mmol/L; multivariate Logistic regression analysis showed that APACHE Ⅱ Score, blood lactate and serum sodium were the independent risk factors for ICU in the treatment of patients with severe infection. Conclusion APACHE Ⅱ score, blood lactate and serum sodium were the independent risk factors for ICU in the treatment of severe infections.
出处
《中国处方药》
2016年第12期5-6,共2页
Journal of China Prescription Drug