摘要
目的评价乳酸及C反应蛋白(CRP)联合检测对重症肺炎的诊断价值。方法检测某院普通肺炎和重症肺炎患者(各40例),以及健康体检者(30例)血清中乳酸及CRP水平,评价其在重症肺炎中的诊断价值。结果重症肺炎组患者血清中乳酸及CRP水平[分别为(9.90+1.30)mmol/L、(80.10+12.30)mg/L]均高于普通肺炎组[分别为(4.90+0.50)mmol/L、(30.20+5.70)mg/L]和健康对照组[分别为(1.20+0.10)mmol/L、(5.01+0.50)mg/L],差异均有统计学意义(均P<0.05)。单独检测乳酸、CRP的灵敏度为75.0%、60.0%,特异度为90.0%、70.0%,联合检测乳酸和CRP的灵敏度为90.0%,特异度为85.7%,联合检测的灵敏度高于单个指标的检测(P<0.05);各组特异度比较,差异无统计学意义(P>0.05)。结论血清乳酸水平在重症肺炎中的诊断价值优于CRP,乳酸和CRP联合检测能够提高灵敏度,而不降低特异度。
Objective To evaluate the combined detection value of lactic acid（LA）and C-reactive protein （CRP）in the diagnosis of severe pneumonia.Methods Serum LA and CRP levels in 40 patients who were diagnosed with or-dinary pneumonia,40 with severe pneumonia,and 30 healthy physical examination subjects （control group）were detected,diagnostic value in severe pneumonia was evaluated.Results Serum LA and CRP levels in patients with severe pneumonia were （9.90 ＋ 1 .30）mmol/L and （80.10 ＋ 12.30）mg/L respectively,which were higher than those in ordinary pneumonia （[4.90＋0.50]mmol/L,[30.20＋5.70]mg/L,respectively）and healthy control group （[1 .20＋0.10]mmol/L,[5.01 ＋0.50]mg/L,respectively）,difference were both significant（both P 〈0.05 ）.The sensitivity of separately detected LA and CRP were 75.0% and 60.0% respectively,specificity were 90.0% and 70.0% respectively,sensitivity and specificity of combined detection of LA and CRP were 90.0% and 85.7% re-spectively,sensitivity of combined detection was higher than that of separate detection（P 〈0.05 ）;specificity of each group was not significantly different （P 〉0.05）.Conclusion The diagnostic value of serum LA level in severe pneumonia is better than that of CRP,combined detection of LA and CRP can improve the sensitivity,but will not decrease specificity.
出处
《中国感染控制杂志》
CAS
北大核心
2016年第11期849-851,871,共4页
Chinese Journal of Infection Control
关键词
乳酸
C
反应蛋白
重症肺炎
肺炎
诊断价值
lactic acid
C-reactive protein
severe pneumonia
pneumonia
diagnostic value
