摘要
胰岛素信号转导通路的正常运行在胰岛素生理作用下发挥重要的作用,炎性细胞因子等干扰胰岛素正常信号转导通路,激活胰岛素抵抗信号转导通路,导致胰岛抵抗并发生2型糖尿病。该文参阅国内外文献,对近年来2型糖尿病胰岛素与胰岛素抵抗信号转导通路进行综述和评价。
The normal operation of the insulin signal pathways play an important role in insulin physiological function. Inflammatory cytokines cause insulin resistance signal pathways by interfering with the insulin signal pathways. And the occurrence of insulin resistance and type 2 diabetes mellitus. Referring to the literaturein China and abroad. The insulin signal pathways and insulin resistance signal pathway of type 2 diabetes mellitus are summarized.
出处
《辽宁中医药大学学报》
CAS
2016年第11期71-73,共3页
Journal of Liaoning University of Traditional Chinese Medicine
基金
国家科技部"十二五"科技支撑计划项目(2014BAI10B00)
关键词
2型糖尿病
胰岛素
胰岛素抵抗
信号转导
type 2 diabetes mellitus
insulin
insulin resistance
signal pathway