摘要
目的探讨近10年广东省人民医院治疗的食管癌患者,分析其发病趋势及内镜、组织病理学特征改变,为食管癌流行病学调查提供参考。方法回顾性分析2005年1月至2014年12月广东省人民医院确诊的1108例食管癌患者的临床资料。对比分析前、后5年所有食管癌患者的发病趋势、内镜、病理组织学分型等差异。结果 1108例食管癌患者,占总胃镜检查人数的1.3%(1 108/87 805);病理分型以鳞癌为主,占92.3%(1 023/1 108);其次为食管腺癌,占4.6%(85/1 108);超过半数(50.9%,564/1 108)的食管癌位于食管下段。前、后5年相比,食管癌检出率比较,无统计学差异(1.2%vs 1.3%),后5年食管腺癌的构成比较前5年明显高,差异有统计学意义(6.5%vs 2.4%,P=0.04)。前、后5年间早期食管癌构成比由4.0%(20/509)上升至5.9%(35/599),差异有统计学意义(P=0.03)。结论 10年间经胃镜食管癌检出率无明显变化,食管癌病理类型仍以鳞癌为主,但近年来食管癌中腺癌的构成比明显增加,侧面反映出华南地区食管腺癌发病率逐渐升高。
Objectives The purpose of the study is to evaluate the trend of clinical characteristics of esophageal carcinoma in the recent 10 years to provide a reference for the investigation of epidemiological data of esophageal carcinoma. Methods Clinical data of 1 108 patients with esophageal cancer diagnosed by esophagogastroduodenoscopy （EGD） in Guangdong General Hospital from Jan. 2005 to Dee. 2014 were collected and analyzed. The patients were divided into two groups by time period, which were that one group from Jan. 2005 to Dec. 2009 and the other from Jan. 2010 to Dec. 2014. Results Generally, the detection rate of esophageal carcinoma was 1. 3%. No significant difference was found between the two periods （ 1.2% vs 1.3% ）. More than half of the location （50.9%） of the tumors was at the lower part of the esophagus, especially the esophageal adenocarcinoma. The main pathological type of esophageal carcinoma remained the squamous cell carcinoma. But the proportion of esophageal adenocarcinoma has increased rapidly in recent 5 years when compared with that in the previous 5 years （6.5% vs 2.4% ,P = 0.04）. The composition of the early esophageal cancer increased from 4. 0% to 5. 9% with statistical significance （ P = 0.03 ）. Conclusions The detection rate of esophageal cancer under gastroscopy has no significant difference from 2005-2014, The main pathological type of esophageal carcinoma is still esophageal squamous cell carcinoma, but the constituent ratio of esophageal adenocarcinoma has increased significantly in recent years, which may reflect the rising incidence of esophageal adenocarcinoma in South China.
出处
《中华胃肠内镜电子杂志》
2015年第3期22-25,共4页
Chinese Journal of Gastrointestinal Endoscopy(Electronic Edition)
关键词
食管肿瘤
流行病学
内窥镜
病理学
Esophageal Neoplasms
Epidemiology
Endoscopes
Pathology
