摘要
目的:调查老年女性骨质疏松症(OP)患者药物治疗的现状,寻找提高老年女性OP患者临床疗效的方法。方法:对172例老年女性OP患者的用药情况进行调查,并分析用药情况与血清骨转换标志物(BTMs)的关系。结果:老年女性OP患者药物治疗率很低,仅为36.05%。接受过抗OP药物治疗的老年女性OP患者的3个BTMs水平均明显低于未接受过药物治疗的患者,差异有统计学意义(P<0.001);坚持(≥12月)抗OP药物治疗老年女性的3个BTMs水平均明显低于未坚持(<12月)治疗的患者,差异有统计学意义(P<0.05)。结论:加强OP防治知识的宣传,提高OP患者的用药依从性,可能是提高老年女性OP患者临床治疗效果的重要方法。
Objective ： To probe into the way to heighten clinic therapeutic effect by means of investigating current status of drug treatment in elderly osteoporosis women, nethods：A cross-sectional survey was conducted comprising a sample of 172 elderly osteoporosis women. All of subjects underwent questionnaire survey and monitoring of bone turnover markers （ BTMs）, and the relationship between pharmacy and BTMs was analyzed. Results： The rate of drug treatment was only 36.05% in elderly osteoporosis women. The lever of BTMs were significantly lower in elderly osteoporosis women who had accepted drug treatment than who hadn＇ t （ P 〈 0. 001 ） ; and the ones were significantly lower in elderly osteoporosis women who had persisted to accept drug treatment （ I〉 12 month） than who hadn＇t （ 〈 12 month） （P 〈 0.05 ）. Conclusion：The probable ways to improve clinic therapeutic effect in elderly osteoporosis women were to strengthen publicity and education of osteoporosis knowledge, and to improve medication adherence.
出处
《药物流行病学杂志》
CAS
2016年第11期719-721,共3页
Chinese Journal of Pharmacoepidemiology
基金
浙江省医药卫生平台重点资助项目(编号:2016ZDA002)
浙江省人民医院优秀青年人员科研启动基金(编号:zry2015C002)
