摘要
目的探讨七氟醚静吸复合麻醉与丙泊酚全凭静脉麻醉用于小儿斜视手术的临床应用效果。方法 选择本院2014年8月～2016年6月全身麻醉下行眼科斜视手术的患儿60例,ASA分级Ⅰ级,其中男患儿26例,女患儿34例,年龄2～6岁。随机数字表法均分为丙泊酚全凭静脉麻醉组（P组）和七氟醚静吸复合麻醉组（S组）,各30例。P组给予丙泊酚＋芬太尼静脉麻醉诱导,丙泊酚＋瑞芬太尼静脉麻醉药物维持。S组七氟醚＋芬太尼麻醉诱导,七氟醚＋瑞芬太尼静脉麻醉药物维持。比较两组诱导前（T1）、插气管导管即刻（T2）、手术开始时刻（T3）、术中15 min（T4）、手术结束时刻（T5）时的平均动脉压（MAP）、心率（HR）、术后拔管时间（T0）及PACU停留时间。结果 插气管导管即刻（T2）P组心率[（115±8）次/min]与S组心率[（107±8）次/min]、手术开始时刻（T3）P组心率[（110±7）次/min]与S组心率[（106±8）次/min]、术中15 min（T4）P组心率[（111±8）次/min]与S组心率[（107±7）次/min]、手术结束时刻（T5）P组心率[（110±7）次/min]与S组心率[（106±8）次/min]比较,差异有统计学意义（P〈0.05）,术后拔管时间（T0）S组[（7.5±2.6）min]短于P组[（9.4±2.7）min]（P〈0.05）。结论 七氟醚静吸复合麻醉术中心率稳定,术后拔管迅速,可安全有效地应用于小儿斜视手术。
Objective To explore the clinical application of sevoflurane static inhalation combined anesthesia and propofol total intravenous anesthesia in pediatric strabismus surgery.Methods 60 children patients who conducted strabismus surgery from August 2014 to June 2016 in our hospital were selected.ASA grade was grade Ⅰ,among that 26 cases were boys,34 cases were girls and the age from 2 to 6 years.Patients were average divided into propofol total intravenous anesthesia group（P group） and sevoflurane static inhalation combined anesthesia group（S group） by random number table,30 cases in each group.Patients in P group were used propofol and fentanyl intravenous anesthesia induction and drug maintenance with propofol and remifentanil intravenous anesthesia.Patients in S group were used sevoflurane and fentanyl intravenous anesthesia induction and drug maintenance with sevoflurane and remifentanil intravenous anesthesia.The mean arterial pressure（MAP）,heart rate（HR）,postoperative extubation time（T0） and PACU residence time at before induction（T1）,the beginning of tracheal intubation（T2）,the beginning of operation（T3）,15 min in operation（T4） and the end of operation（T5） in two groups were compared.Results The heart rate in P group at the beginning of tracheal intubation（T2）,the beginning of operation（T3）,15 min in operation（T4） and the end of operation（T5） were respectively [（115 ±8）/min], [（110 ±7）/min], [（111 ±8）/min] and [（110 ±7）/min],which had statistical significances with those were respectively [（107 ±8）/min], [（106 ±8）/min], [（107 ±7）/min] and [（106 ±8）/min] in S group（P〈0.05）.The postoperative extubation time（T0） was [（7.5±2.6）min] in S group,shorter than that was [（9.4±2.7）min] in P group（P〈0.05）.Conclusion Sevoflurane static inhalation combined anesthesia can stabilize heart ratio during operation,rapid extubate after operation and can be safely used in pediatric strabismus surgery.
出处
《中国当代医药》
2016年第32期112-114,共3页
China Modern Medicine
