摘要
目的研究奥美拉唑在呼吸衰竭并发消化道出血治疗中的临床效果。方法选取我院2014年8月-2016年9月收治的60例呼吸衰竭并发消化道出血患者,依据患者入院就诊时间随机分为对照组（n=30）与研究组（n=30）,对照组给予静脉注射西咪替丁,研究组给予静脉注射奥美拉唑,对比分析两组患者经不同方式治疗后的临床疗效。结果两组患者经治疗后,研究组无效2例,总有效率93.33%,研究组中有1例发生不良反应,不良反应发生率3.33%,对照组中有7例发生不良反应,不良反应发生率23.33%,研究组总有效率与不良反应发生率优于对照组,χ-2=6.666 7,5.192 3,P〈0.05,差异有统计学有意义。结论奥美拉唑应用于呼吸衰竭并发消化道出血治疗过程中具有显著效果,可降低不良反应率,提高治疗依从性。
Objective To study the clinical effect of omeprazole in the treatment of respiratory failure complicated with gastrointestinal bleeding. Methods 60 cases of respiratory failure complicated with gastrointestinal bleeding in our hospital from August 2014 to September 2016 were selected, according to the time of admission, the patients were randomly divided into control group（n=30） and study group（n=30）, the control group was given intravenous injection of cimetidine, the study group was given intravenous omeprazole, the clinical effect of two groups of patients after treatment were compared and analyzed. Results Two groups of patients after treatment, the study group was ineffective in 2 cases, the total effective rate of 93.33%, adverse reactions occurred in 1 patients in the study group, and the incidence of adverse reactions was 3.33%, adverse reactions occurred in 7 cases of control group, the incidence of adverse reactions was 23.33%, the total effective rate and adverse reaction rate of the study group was better than that of the control group, χ-2=6.666 7, 5.192 3, P 0.05, the difference was statistically significant. Conclusion Omeprazole has asignificant effect in the treatment of respiratory failure complicated with gastrointestinal bleeding, which can reduce the adverse reaction rate and improve the treatment compliance.
出处
《中国继续医学教育》
2016年第31期176-177,共2页
China Continuing Medical Education
关键词
奥美拉唑
呼吸衰竭
消化道出血
临床效果
Omeprazole
Respiratory failure
Gastrointestinal bleeding
Clinical effect
