摘要
目的 探讨空气颗粒物PM2.5和女性急性心肌梗死（AMI）病发的相关性。方法 连续收集2011-2013年就诊于吉林大学中日联谊医院的急性心肌梗死患者,均记录血常规、凝血常规、肝功以及血脂等相关信息。同期吉林地区的空气污染指数来源于我国环境保护部发表的数据。结果 比较男女患者的生理指标发现血小板、血红蛋白以及白蛋白指数有很大差异。根据我国环境保护部发表的数据,在所有统计天数中仅6 d空气中主要污染物为二氧化硫,其余均为颗粒物污染。试验发现颗粒物污染指数与AMI急诊人群的病发年龄呈负相关,即颗粒物污染越严重心肌梗死的病发年龄越低（OR=0.06;95%CI：0.009~0.44;P=0.005）,而且此相关性在女性中极为显著（OR=0.02;95%CI：0.001~0.25;P=0.003）。证明了颗粒物污染指数对AMI病发年龄的影响具有即时性,同时亦有性别差异。结论 研究结果表明空气颗粒物PM2.5和女性急性心肌梗死病发的相关性。
Objective To explore the correlation between PM2. 5 and onset of acute myocardial infarction among female patients. Methods The patients with acute myocardial infarction were selected from China-Japan Union Hospital of Jilin University from 2011 to 2013. The results of routine blood test, routine coagulation test, live function, and blood lipids were recorded. Air pollution index in Jilin ar- ea during the same period was from Ministry of Environmental Protection. Results There were significant differences in blood platelets, he- moglobin, and albumin index between male patients and female patients. According to the data from Ministry of Environmental Protection, the main pollutant in air within 6 days was sulfur dioxide, while the rest was particulate. Particulate pollution index was negatively correlated with onset age of patients with acute myocardial infarction, the severer particulate pollution was, the younger onset age of acute myocardial infarction was （ OR=O. 06, 95% CI： 0. 009-0. 44, P= 0. 005 ） , the correlation was significant among female patients （ OR = 0.02, 95% CI： 0. 001-0. 25, P=0. 003） . The effect of particulate pollution index on onset age of acute myocardial infarction had instantaneity and gender difference. Conclusion The study indicates the correlation between PM2. 5 and onset of acute myocardial infarction among female patients.
出处
《中国妇幼保健》
CAS
2016年第22期4626-4629,共4页
Maternal and Child Health Care of China
基金
吉林省级产业创新专项资金项目(2016C041)
关键词
空气颗粒物
PM2.5
心肌梗死
Air particulate
PM2. 5
Acute myocardial infarction
