摘要
目的探讨胃肠胰神经内分泌肿瘤(GEP-NENs)的影像表现及其病理特征。方法回顾性分析48例经病理证实为GEP-NENs患者的影像及临床资料,其中33例胃肠道NENs患者均接受CT检查;15例胰腺NENs患者中,9例只接受CT检查,4例只接受MR检查,2例同时接受CT及MR检查。分析其影像学表现及病理特征。结果48例GEP-NENs患者中,15例(15/48,31.25%)位于胰腺,其次为胃部12例(12/48,25.00%)和直肠11例(11/48,22.92%),其他部位较少见。G1级12例(12/48,25.00%),G2级11例(11/48,22.92%),G3级20例(20/48,41.67%),混合腺NENs有5例(5/48,10.42%)。突触素阳性46例(46/48,95.83%),嗜铬粒蛋白A阳性36例(36/48,75.00%)。胰腺NENs主要位于胰头及体尾部,大小、形状、生长方式不一,可有囊变坏死及钙化;CT平扫呈等或低密度;MR平扫T1WI为等(低)信号,T2WI为等(高)信号,增强后强化方式多样。33例胃肠NENs CT平扫可见管壁增厚或局部软组织结节、肿块影;增强扫描12例(12/33,36.36%)呈均匀中度强化,11例(11/33,33.33%)呈不均匀且不规则强化。结论胰腺、胃、直肠是GEP-NENs的好发部位,其临床症状及影像表现均不具特异性。
Objective To explore the imaging and clinicopathologic features of gastroenteropancreatic neuroendocrine neoplasms（GEP-NENs）.Methods Images and clinical datum of 48GEP-NENs patients confirmed by pathology were retrospective analyzed.Thirty-three gastrointestinal NENs patients all underwent CT examination.Among 15 pancreatic NENs patients,9cases only underwent CT examination,4cases only underwent MR examination,2cases underwent CT and MR examination.Image and pathology evaluation were carried out.Results Fifteen（15/48,31.25%）of 48GEP-NENs patients was in pancreas,and 12patients（12/48,25.00%）were in stomach,11patients（11/48,22.92%）were in rectum,rest parts rarely occurred.There were 12cases（12/48,25.00%）G1grade,11cases（11/48,22.92%）G2grade,20cases（20/48,41.67%）G3grade,5cases（5/48,10.42%）mixed gland NENs.There were synaptophysin positive 46cases（46/48,95.83%）and chromogranin A positive 36cases（36/48,75.00%）.Pancreatic NENs were mainly located in the head,body and tail of pancreas,with different sizes,morphology and growth patterns.Necrosis and calcification were seen in the tumors.CT plain scan showed iso-density or low-density.MR T1 WI showed iso-intensity（hypo-intensity）,and T2 WI showed iso-intensity（hyper-intensity）.Enhanced MR showed various enhanced patterns.CT plain scan images of 33 gastrointestinal NENs mainly showed thickening walls or nodules and masses in local area,and enhanced CT scan mainly showed moderately homogeneous enhancement in 12patients（12/33,36.36%）or irregularly heterogeneous enhancement in 11patients（11/33,33.33%）.Conclusion GEP-NENs mainly occurs in pancreas,stomach and rectum,and its clinical symptoms and imaging finding are nonspecific.
出处
《中国医学影像技术》
CSCD
北大核心
2016年第11期1701-1705,共5页
Chinese Journal of Medical Imaging Technology
关键词
胃肠胰神经内分泌肿瘤
体层摄影术
X线计算机
磁共振成像
Gastroenteropancreatic neuroendocrine neoplasms
Tomography
X-ray computed
Magnetic resonance imaging
