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胺碘酮联合美托洛尔静脉注射治疗快速心律失常的临床疗效观察 被引量:7

Clinical effect observation of amiodarone combined with metoprolol intravenous injection in treatment of tachyarrhythmia
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摘要 目的 分析探讨胺碘酮联合美托洛尔静脉注射治疗快速心律失常的临床疗效。方法 选取2014年6月~2016年4月期间我院收治的77例快速心律失常患者,采用随机数字表法分为观察组(n=39)和对照组(n=38)。对照组采用胺碘酮治疗,观察组采用胺碘酮联合美托洛尔静脉注射治疗。分析比较两组患者的各项治疗指标、治疗有效率、窦性心律转复率、复发率和并发症发生率。结果 治疗前,两组患者的收缩压、舒张压、HR比较无统计学意义(P〉0.05);治疗后,观察组患者的收缩压、舒张压、HR和对照组患者的收缩压、HR显著降低,观察组患者的起效时间、收缩压、舒张压、HR均小于对照组,差异有统计学意义(P〈0.05);观察组患者的治疗有效率和窦性心律转复率高于对照组,复发率和并发症发生率小于对照组,差异有统计学意义(P〈0.05)。结论 胺碘酮联合美托洛尔静脉注射治疗快速心律失常疗效显著,值得推广使用。 Objective To analyze the clinical efficacy of amiodarone combined with metoprolol intravenous injection in treatment of tachyarrhythmia. Methods 77 cases of rapid arrhythmia in our hospital from June 2014 to April 2016 were selected and they were randomly divided into observation group and control group. Patients in control group were treated with amiodarone therapy, and patients in observation group were treated with amiodarone combined with metoprolol intravenous injection treatment. The treatment index, treatment efficiency, sinus rhythm conversion rate, recurrence rate and incidence of complications between two groups were analyzed and compared. Results There were no statistical significances on systolic blood pressure, diastolic blood pressure and HR between the two groups before the treatment. After treatment, the SBP, DBP, HR in observation group were significantly reduced, compared with the control group. The onset time, SBP, DBP, HR in observation group were significantly less than those in control group, and the difference was statistically significant (P 〈 0.05). The treatment efficiency and sinus rhythm cardio version rate in observation group were higher than those in control group, the recurrence rate and complication rate were lower than the control group, and the difference was statistically significant (P 〈 0.05). Conclusion Intravenous amiodarone combined with metoprolol in treating rapid arrhythmia has significant curative effect. It is worth popularizing.
出处 《中国医药科学》 2016年第17期81-83,共3页 China Medicine And Pharmacy
关键词 胺碘酮 美托洛尔静脉注射 快速心律失常 Amiodarone metoprolol Intravenous injection Rapid arrhythmia
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