摘要
目的探讨合理运用降压药物对高血压病合并急性脑梗死患者血压控制和肢体功能康复的影响。方法将本院收治的84例高血压病合并急性脑梗死患者按照患者(或家属)意愿,分为观察组和对照组各42例;对照组采用常规脑梗死治疗措施;观察组在常规治疗的同时,合理运用降压药物,连续使用8周,并随访1年;比较2组治疗前后的血压控制情况、肢体功能评分(FMA评分和Barthel评分),记录2组病情加重率和复发率。结果观察组血压控制率显著高于对照组(P<0.05);治疗第12、24、48周后观察组FMA和Barthel评分均显著高于对照组(P<0.05);观察组1年内病情加重率和复发率均显著低于对照组(P<0.05)。结论高血压病合并脑梗死患者合理运用降压药物能够显著控制血压,改善肢体功能,降低复发率和加重率。
ObjectiveTo explore the effect of antihypertensive drugs on blood pressure control and limb function rehabilitation in patients with hypertension and initial cerebral infarction.Methods 84 cases of hypertension patients with primary cerebral infarction were divided into the observation group and the control group according to the wishes of the patients（or their family members）. The control group was treated as routine cerebral infarction. Based on conventional treatment, 8 weeks rational use of antihypertensive drugs was used at the same time in the observation group. Blood pressure control situation, limb function score（FMA score and Barthel score）were compared between the two groups after 8 weeks, and the two groups were followed up for 1 years. The rate of disease exacerbation and recurrence rate were recorded.Results the control rate of blood pressure in the observation group was significantly higher than in the control group（P〈0.05）. After 12, 24, 48 weeks of treatment, FMA and Barthel scores in observation group were significantly higher than the control group, the difference was statistically significant（P〈0.05）. In the observation group, the rate of exacerbation rate and recurrence rate were significantly lower than those of the control group（P〈0.05）.Conclusion the rational use of antihypertensive drugs in patients with hypertension and cerebral infarction can significantly control blood pressure, improve limb function, reduce the rate of recurrence and exacerbation rate, it is worthy of clinical application.
出处
《卒中与神经疾病》
2016年第5期329-332,共4页
Stroke and Nervous Diseases
基金
2014年度镇江市科技支撑(社会发展)指导性项目合同(PZ2015044)
关键词
首发脑梗死
高血压
降压药
肢体功能康复
First episode cerebral infarction Hypertension Antihypertensive drugs Limb function rehabilitation
