摘要
目的：评价间歇式充气加压仪（ IPC）在预防脊柱术后深静脉血栓（ DVT）中的应用价值。方法计算机检索Cochrane Library、PubMed、CNKI、万方数字期刊群等关于IPC预防脊柱术后深静脉血栓的随机对照试验（ RCT）。对随机对照试验的质量进行严格评价,数据由2名评价员独立提取,按照纳入排除标准筛选和提取文献,并采用Stata 12.0软件进行Meta分析。结果 Meta分析结果显示,IPC组与空白对照组DVT发生率比较[RR＝0.11,95％CI（0.04,0.34）,P＝0.921],IPC与低分子肝素合用组DVT发生率与低分子肝素组比较[RR＝0.27,95％CI（0.12,0.61）,P＝0.97],IPC与分级加压弹力袜组DVT发生率与单纯使用分级加压弹力袜组DVT发生率比较（χ2＝3.871,P〈0.05）,差异均有统计学意义；而IPC组与低分子肝素组DVT的发生率比较差异无统计学意义（ P〉0.05）；通过研究报告的验证,IPC使用更安全。结论采用IPC能有效预防DVT,减少脊柱外科术后患者DVT发生率。但由于纳入研究质量不高,样本含量较少,仍需大样本、高质量的临床随机对照试验来验证。
Objective To evaluate the application value of intermittent pneumatic compression （ IPC） in preventing deep vein thrombosis （ DVT ） after spinal operation. Methods Randomized controlled trails （ RCTs） on ICP in preventing DVT were searched in the Cochrane Library, PubMed, CNKI, Wanfang data and so on. Quality of RCTs was evaluated strictly. Data were extracted by two researchers. Literature was selected and extracted according to inclusion and exclusion criteria. And then, Meta-analysis was used to analyze the data with the software Stata 12.0.Results Meta-analysis results revealed much on the incidences comparison of DVT between the IPC group and the blank control group [RR=0.11, 95% CI（0.04, 0.34）, P=0.921], among the ICP group and low-molecular-weight heparin group with the low molecular heparin group [ RR=0. 27, 95% CI （ 0.12, 0.61） , P=0.97] , among the ICP group and graduated compression stocking group with the group using graduated compression stocking alone （χ2=3.871, P〈0.05） with significant differences. However, there was no statistically significant difference in the incidence of DVT between the ICP group and the low molecular heparin group （P〉0. 05）. The use of IPC was safe by the confirmation of research report. Conclusions IPC can effectively prevent DVT and reduce the incidence of DVT of postoperative patients in department of spine surgery. However, the clinical RCTs with large sample size and high quality are needed to validate since the included studies with low quality and small sample size.
出处
《中华现代护理杂志》
2016年第26期3775-3778,共4页
Chinese Journal of Modern Nursing
