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胰岛素样生长因子结合蛋白7在相关皮肤病中的研究新进展 被引量:2

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摘要 胰岛素样生长因子结合蛋白7 (IGFBP7)是20世纪90年代研究发现的一种胰岛素样生长因子结合蛋白,它是胰岛素样生长因子结合蛋白超家族16种结合蛋白中的1种,除了能与胰岛素样生长因子结合发挥作用外,因其对胰岛素有较高的亲和性,故在人体内还具有调节胰岛素的分布及新陈代谢等作用,同时,它还能与胰岛素受体结合,它是一种功能性的胰岛素结合蛋白.
出处 《重庆医学》 CAS 北大核心 2016年第31期4440-4443,共4页 Chongqing medicine
基金 三峡大学人才基金资助项目(KJ2011B081) 湖北省宜昌市社会发展基金资助项目(宜科发[2013]23号A13301-41)
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  • 1RUAN Wen-jing,LIN Jie,XU En-ping,XU Fang-ying,MA Yu,DENG Hong,HUANG Qiong,LV Bing-jian,HU Hu,CUI Jing,DI Mei-juan,DONG Jian-kang,LAI Mao-de.Science Letters:IGFBP7 plays a potential tumor suppressor role against colorectal carcinogenesis with its expression associated with DNA hypomethylation of exon 1[J].Journal of Zhejiang University-Science B(Biomedicine & Biotechnology),2006,7(11):929-932. 被引量:11
  • 2Wajapeyee N, Serra R W, Zhu X, et al. Oncogenic BRAF induces senescence and apoptosis through pathways media- ted by the secreted protein IGFBP7[J]. Cell, 2008, 132(3): 363-374. 被引量:1
  • 3Chen R Y, Chen H X, Lin J X, et al. In-vivo transfection of pcDNA3.1-IGFBP7inhibits melanoma growth in mice through apoptosis induction and VEGF downexpression[J]. J Exp Clin Cancer Res. 2010,29:13. 被引量:1
  • 4Chen R Y, Chen H X, Jian P, et al. Intratumoral injection of pEGFCI-IGFBP7 inhibits malignant melanoma growth in C57BL/6J mice by inducing apoptosis and down-regulating VEGF expression[J]. Oncol Rcp. 2010,23(4):981-988. 被引量:1
  • 5Tamura K, Hashimoto K, Suzuki K, et al. Insulin-like growth factor binding protein-7 (IGFBP7) blocks vascular endothe- lial cell growth factor (VEGF)-induced angiogenesis in human vascular endothelial cells[J]. Eur J Phannacol, 2009, 610(1-3):61-67. 被引量:1
  • 6Kanemitsu N, Kato M V, Mild T, et al. Characterization of the promoter of the murine mac25 gene[J]. Bioehem Biophys Res Commtm, 2000, 279(1):251-257. 被引量:1
  • 7Bustin S A, Jenkins P I. The growth hormone-insulin-like growth factor-I axis and colorectal cancer[J]. Trends Mol Med, 2001, 7(10):447-454. 被引量:1
  • 8Di Popolo A, Memoli A, Apicella A, et al. IGF-II/IGF-I receptor pathway up-regulates COX-2 mRNA expression and PGE2 synthesis in Caco-2 human colon carcinoma cells[J]. Oncogene, 2000,19(48):5517-5524. 被引量:1
  • 9Burger A M, Leyland-Jones B, Banerjee K, et al. Essential roles of !GFBP-3 and IGFBP-rP1 in breast eaneer[J].Eur J Cancer, 2005, 41(11):1515-1527. 被引量:1
  • 10Sato Y, Chen Z, Miyazald K. Strong suppression of tumor growth by insulin-like growth factor-binding protein-related protein 1/tumor-derived cell adhesion factor/mac25[J]. Cancer Sci, 2007,98(7): 1055-1063. 被引量:1

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