摘要
In this issue of PNAS,Wei and colleagues demonstrate that the Nuclear factor erythroid 2-related factor 2(Nrf2),a well-known cell-intrinsic cytoprotective factor and critical regulator of the anti-oxidant response plays an important function in reparative angiogenesis by suppressing the antiangiogenic effects of Semaphorin 6A(Sema6A),a membrane-associated guidance molecule expressed
In this issue of PNAS, Wei and colleagues demonstrate that the Nuclear factor erythroid 2-related factor 2 （Nrf2）, a well-known cell-intrinsic cytoprotective factor and critical regulator of the anti-oxidant response plays an important function in reparative angiogenesis by suppressing the antiangiogenic effects of Semaphorin 6A （Sema6A）, a membrane-associated guidance molecule expressed by neurons during retinal ischemia （1）.
基金
supported by the Heart and Stroke Foundation of Canada(HSCF)
the Canadian Stroke Network(CSN)
