摘要
目的:调查高校入学新生ALT升高的情况及其原因。方法:选择2015年夏季入学新生7 757人,其中男生3 069人,女生4 688人;采集空腹静脉血并分离血清,在迪瑞DIRUICS-600B全自动生化分析仪上,采用速率法(仪器配套试剂)测定ALT,同时用酶联免疫法检测乙型肝炎病毒抗原和抗体。针对ALT≥80 U/L的新生进行问卷调查,分析升高原因。结果:在7 757份血清中,ALT≥80 U/L有105例,占1.35%;男生76例,占2.48%,女生29例,占0.62%,男女之间有显著性差异(x^2=47.94,P<0.001)。对105例新生进行了问卷调查,发现体重超重(体重指数BMI≥24)占15.2%(16/105),肥胖(BMI≥28)占24.8%(26/105);另外,脂肪肝占15.2%(16/105);有明显熬夜占35.3%(37/105);采血前一周内有"感冒史"占23.8%(25/105);少数为乙肝病毒携带者8例(7.6%)和剧烈运动7例(6.3%)及其它原因。结论:高校入学新生ALT升高主要是体重超重肥胖、熬夜和"感冒"三种原因引起为主,少数为乙型肝炎病毒携带者和剧烈运动。
Objective： The aims of this study are to investigate the prevalence of elevated alanine aminotransferase and to assess the possible risk factors.Methods： We collect fasting serum samples from 7757 Chinese college freshmen including 3069 boys and 4688 girls. ALT was detected with rate method in Dirui DIRUICS-600B automatic biochemical analyzer, while hepatitis B virus antigens and antibodies are detected with ELISA（enzyme-linked immunosorbent assay）. Then we finished questionnaires about abnormal ALT in freshmen for searching reasons. Results： In 7757 samples, ALT≥80 U/L 105 cases, accounting for 1.35%; men 76 cases, accounting for 2.48%, female 29 cases, accounting for 0.62%, there is a significant difference between men and women （χ2=47.94, P〈0.001）.The questionnaires in 105 students ALT≥80 U/L revealed that BMI〉25,staying up, cold history within one week are first three risks, respectively accounted for 37.1% （39/105）, 35.3% （37/105）, 23.8% （25/105）. We found it that overweight （BMI BMI≥24） accounted for 15.2% （16/105）, obesity （BMI≥28） accounted for 24.8% （26/ 105）. Besides, hepatitis B virus （8eases,7.6%）and strenuous exercise （7cases, 6.3% ） also could affect ALT level. Conclusion： College freshmen increased ALT is mainly caused by obesity, staying up late at night, and ＂cold＂, and partly caused by the hepatitis B virus carriers, and strenuous exercise.
出处
《金华职业技术学院学报》
2016年第6期79-82,共4页
Journal of Jinhua Polytechnic
关键词
高校新生
谷丙转氨酶
脂肪肝
college freshmen, alanine aminotransferase, fatty liver
