摘要
目的:探究缺血性脑血管病患者高尿酸血症与颅内动脉粥样硬化性狭窄的相关性。方法:对120例缺血性脑血管病患者进行颈部血管彩超检查,同时检测血尿酸、血糖、血脂水平。根据颈部血管彩超结果,分为狭窄组和无狭窄组(对照组),狭窄组再根据其动脉狭窄程度分为轻、中、重度狭窄组,用非条件Logistic回归分析评价颅内动脉粥样硬化性狭窄的相关危险因素,并比较颅内动脉不同狭窄程度间的血尿酸水平。结果:除年龄、高血压、糖尿病、血脂异常等已知危险因素外,高尿酸血症是颅内动脉粥样硬化性狭窄的独立危险因素(OR=2.016,P=0.031)。各组血尿酸水平之间比较差异有统计学意义(P<0.05)。结论:高尿酸血症是颅内动脉粥样硬化性狭窄的独立危险因素,且尿酸水平可提示狭窄的严重程度。
Objective： To investigate the correlation between the degrees of intracranial atherosclerotic stenosis and hyperuricemia in patients with ischemic cerebrovascular disease.Methods： A total of 120 patients with ischemic cerebrovascular disease received ultrasonography examination of cervical blood vessels, their t^c acid, blood glucose, blood lipids were detected. They were divided into stenosis group （including mild stenosis group, moderate stenosis group and severe stenosis group）, and non-stenosis group （control group）. The related risk factor for the degree of intracranial atherosclerotic stenosis was analyzed by unconditioned Logistic regression analysis, comparing the differences of uric acid level in intracranial artery stenosis. Results： Excluding the known risk factors such as age, high blood pressure, diabetes, and dyslipidemia, hyperuricemia is an independent risk factor for intracranial atherosclerotic stenosis （OR =2. 016, P = 0. 031）, with significantly difference in uric acid level （ P 〈 0. 05）.Conclusions： Hyperuricemia is an independent risk factor ofintracranial atherosclerotic stenosis, and uric acid level can present the severity ofstenosis.
作者
黄惠英
佐小丽
唐凌雯
熊毅佳
谢孟桥
李晓霞
Jia Hu
Huiying Huang Xiaoli Zuo Linwen Tang Yi Xiong Jia Hu Menlo Xie Xiaoxia Li(Department of Neurology, People＇ s Hospital organ, Leshan, Sichuan 614000, China)
出处
《西藏医药》
2016年第4期11-13,共3页
Tibetan Medicine
关键词
高尿酸血症
动脉粥样硬化性狭窄
血尿酸
Hyperuricemia
Intracranial Atherosclerotic Stenosis
Uric Acid
