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超声心动图参数与急性肺栓塞患者预后的相关性分析 被引量:14

The correlation analysis of echocardiographic parameters and outcomes in patients with acute pulmonary embolism
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摘要 目的评价急性肺栓塞(APE)患者超声心动图参数与预后的相关性。方法选取276例APE患者,离线测量患者的超声心动图资料,评估各参数与APE患者死亡率、住院时间、临床恶化的相关性。结果Cox回归分析表明,左心室舒张期末内径(LVEDD,HR=0.56。95%C10.39~0.81)、右心室/左心室舒张期末内径比值(RVEDD/LVEDD,HR=1.09,95%CI1.02—1.17)、三尖瓣环平面收缩漂移(TAPSE,HR=0.54,95%C10.32~0.91)、左心室射血分数(LVEF,HR=0.80,95%C10.63—0.98)与患者长期全因死亡率相关。室中隔(IVS)左移(HR=3.17,95%CI1.36~6.81)、右心室壁厚(RVWT,HR=1.20,95%CI1.06—1.36)与患者总住院时间相关。结论采用超声心动图多参数指标对APE患者进行评估,可初步预测患者的预后。 Objective To evaluate the correlation of echocardiographic parameters and outcomes in patients with acute pulmonary embolism (APE). Methods A total of 276 patients with APE treated in our hospital were included. Patients echocardiographic data were measured off - line. The correlation of echocardiographic parameters and mortality, length of stay, clinical deterioration was analyzed. Results Cox regression analysis showed that left ventricular end - diastolic diameter ( LVEDD, HR = 0. 56, 95% CI 0. 39 - 0. 81 ), right ventricular/left ventricular end - diastolic diameter ( RVEDD/ LVEDD, HR = 1.09, 95%CI 1.02 ~ 1.17), tricuspid annular plane systolic excursion (TAPSE, HR = 0.54, 95% CI 0.32 - 0.91 ), left ventricular ejection fraction ( LVEF, HR = 0.80, 95% CI 0.63 0.98) were related to long - term all - cause mortality. Leftward shifting of the interventricular septum ( IVS, HR = 3.17, 95% CI 1.36 - 6.81 ), right ventricular wall thickness ( RVWT, HR = 1.20, 95% CI 1.06 - 1.36) were related to length of total hospital stay. Conclusion Evaluation of patients with acute pulmonary embolism by echocardiography multi -parameter indicators can preliminary forecast the outcomes of APE patients.
出处 《中国急救医学》 CAS CSCD 北大核心 2016年第10期935-939,共5页 Chinese Journal of Critical Care Medicine
关键词 急性肺栓塞(APE) 预后 超声心动图 Acute pulmonary embolism(APE) Prognosis Echocardiography
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