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Broad H3K4me3 as A Novel Epigenetic Signature for Normal Development and Disease

Broad H3K4me3 as A Novel Epigenetic Signature for Normal Development and Disease
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摘要 The breadth of the enrichment site for post-translational trimethylation of histone H3 at lysine 4 (H3K4me3) on chromatin has attracted great attention recently. H3K4me3, an extensively-studied histone modification, is reported to promote gene transcription by directing preinitiation complex assembly through interaction with effector proteins, e.g., The breadth of the enrichment site for post-translational trimethylation of histone H3 at lysine 4 (H3K4me3) on chromatin has attracted great attention recently. H3K4me3, an extensively-studied histone modification, is reported to promote gene transcription by directing preinitiation complex assembly through interaction with effector proteins, e.g.,
出处 《Genomics, Proteomics & Bioinformatics》 SCIE CAS CSCD 2016年第5期262-264,共3页 基因组蛋白质组与生物信息学报(英文版)
基金 supported by faculty start up funding provided by The Methodist Hospital Research Institute,Texas,United States
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