摘要
The breadth of the enrichment site for post-translational trimethylation of histone H3 at lysine 4 (H3K4me3) on chromatin has attracted great attention recently. H3K4me3, an extensively-studied histone modification, is reported to promote gene transcription by directing preinitiation complex assembly through interaction with effector proteins, e.g.,
The breadth of the enrichment site for post-translational trimethylation of histone H3 at lysine 4 (H3K4me3) on chromatin has attracted great attention recently. H3K4me3, an extensively-studied histone modification, is reported to promote gene transcription by directing preinitiation complex assembly through interaction with effector proteins, e.g.,
基金
supported by faculty start up funding provided by The Methodist Hospital Research Institute,Texas,United States