摘要
目的：分析肺癌放化疗患者放化疗期间营养状况，为肺癌放化疗患者营养干预提供依据。方法选择55例行放化疗的肺癌住院患者，应用实验室检查数据对患者入院时、放疗中期及放疗结束进行营养评估，观察放化疗期间营养状况。结果患者入院时血红蛋白（Hb）、白蛋白（ALB）、体质量、体质量指数（BMI）分别为（130．50±17．80）g／L、（41．02±5．68）g／L、（61．29±8．75）kg、（22．36±2．78）kg／m2，放疗中期分别为（115．90±19．00）g／L、（37．94±5．55）g／L、（59．95±9．05）kg、（21．86±2．86）kg／m2，放疗结束分别为（110．40±19．40）g／L、（36．91±5．30）g／L、（58．91±9．30）kg、（21．48±2．99）kg／m2；在放疗不同阶段，其营养指标逐渐下降，Hb 在放疗中期与入院时、放疗后期与中期、放疗后期与入院时比较，差异均有统计学意义（t ＝8．611，P ＜0．05；t ＝2．492，P ＜0．05；t ＝8．185，P ＜0．05）；ALB 在放疗中期与入院时、放疗后期与入院时相比，差异有统计学意义（t ＝3．663，P ＜0．05；t ＝4．815，P ＜0．05），放疗后期患者的 ALB 虽低于放疗中期，但差异无统计学意义（t ＝1．464，P ＞0．05）；体质量在放疗中期与入院时、放疗后期与中期、放疗后期与入院时相比，虽有不同程度下降，但差异无统计学意义（t ＝0．781，P ＞0．05；t ＝0．601，P ＞0．05；t ＝1．382，P ＞0．05）；体质量指数放疗中期与入院时、放疗后期与中期、放疗后期与入院时相比，虽有不同程度下降，但差异无统计学意义（t ＝0．0908，P ＞0．05；t ＝0．690，P ＞0．05；t ＝1．599，P ＞0．05）。三个不同放疗阶段肺癌患者，尤以 Hb（F ＝16．643，P ＝0．000）和 ALB（F ＝7．736，P ＝0．001）下降明显。结论肺癌患者放化疗期间存在营养不良风险，以中后期最为明显�
Objective To provide the nurse care evidence of nutritional intervention in patients with lung cancer during radiotherapy and chemotherapy by analyzing the nutritional status of these patients.Methods 55 patients with lung cancer who received chemotherapy and radiotherapy were selected.The nutritional status of these＆amp;nbsp;patients were evaluated by laboratory examination data at the time of hospitalized,ongoing and the end of radiotherapy. Results The hemoglobin（Hb）,albumin（ALB）,body mass and body mass index（BMI）were （130.50 ±17.80）g/L, （41.02 ±5.68）g/L,（61.29 ±8.75）kg,（22.36 ±2.78）kg/m2 respectively at admission;（115.90 ±19.00）g/L, （37.94 ±5.55）g/L,（59.95 ±9.05 ）kg,（21.86 ±2.86）kg/m2 respectively during the course of radiotherapy;（110.40 ±19.40）g/L,（36.91 ±5.30）g/L,（58.91 ±9.30）kg,（21.48 ±2.99）kg/m2 respectively at the end of radiotherapy.At different stages of radiotherapy,the nutritional index gradually decreased,the Hb was lower in the middle of the radiotherapy than on admission,the difference was significant（t =8.611,P 〈0.05）.The Hb in the late stage of radiotherapy was lower than the middle,the difference was significant（t =2.492,P 〈0.05）.Although the ALB in the latter stage of radiotherapy was lower than the middle,but the difference was not statistically significant （t =1.464,P 〉0.05）,and the difference was significant compared with on admission（t =4.815,P 〈0.05）.The weight of the patients in the middle period of radiotherapy was less than the time of admission,but the difference was not statistically significant（t =0.781,P 〉0.05）.The weight of patients in the late stage of radiotherapy was lower than the medium term,but the difference was not statistically significant as well（t =0.601,P 〉0.05）,and there was no significant difference compared with on admission（t =1.382,P 〉0.05）.The BMI of the patients with radiotherapy was lower than that at the time of admission,the difference was not
出处
《中国基层医药》
CAS
2016年第22期3373-3377,共5页
Chinese Journal of Primary Medicine and Pharmacy
基金
浙江省医药卫生科技计划项目（2012KYA024）
关键词
放射疗法
药物疗法
肺肿瘤
营养评价
Radiotherapy
Drug therapy
Lung neoplasms
Nutrition assessment
