摘要
目的:探讨高危型人乳头状瘤病毒感染者中血清硒、铜及叶酸含量的变化情况.方法:用原子吸收光谱法,检测南疆维吾尔族已婚女性217例人乳头状瘤病毒感染者(病例组)及106例HPV阴性者(对照组)血清中的硒、叶酸及铜含量.统计学方案采用logistic回归t检验.结果:HPV感染者血清中的硒、叶酸含量较非感染者低(P<0.05).血清中铜含量的检测值于两组之间无统计学差异(P>0.05).结论:南疆维吾尔族女性人乳头状瘤病毒感染的发生与缺硒和叶酸的缺乏有关,对人乳头状瘤病毒感染者适当地补充人体必需的微量元素可能是治疗HPV持续感染的一种合理有效的治疗手段.
Aim：To study the serum selenium,copper contents and folic acid levels in the serum of HPV infected women who live in south Xinjiang of P.R.of China.Methods：The serum levels of Cu,Se and folic acid in 21 7 HPV infected patients were determined by using graphite furnace atomic absorption Spectrometry.Another 1 06 healthy women were chosen as control group.Results：Statistically lower serum level of selenium and folic acid were observed in HPV infected women,while it was found that there was no statistical difference between two groups of women in serum copper contents.Conclusion：Lower serum levels of Se and folic acid might be related to the pathogenesis of HPV infection,and appropriate supplement of the trace elements might be helpful and effective in the treatment of the disease.
出处
《暨南大学学报（自然科学与医学版）》
CAS
CSCD
北大核心
2016年第5期411-415,共5页
Journal of Jinan University(Natural Science & Medicine Edition)
基金
国家自然科学基金项目(81272335)
关键词
人乳头瘤病毒
血清
铜
硒
叶酸
human papilloma virus
serum
copper
selenium
folic acid
