摘要
近年来，食管胃结合部腺癌（AEG）的全球发病率呈上升趋势，而外科治疗在其综合治疗中仍占据最为重要的地位。但由于肿瘤部位和生物学行为的特殊性，在包括术前分型分期、手术径路、淋巴结清扫和切除范围在内的诸多外科问题上尚存在争议。新的TNM分期体系对于该部位肿瘤分期有新的界定，而传统的Siewert分型仍是目前决定外科手术策略较为关键的分型方法。相对于Siewert Ⅰ型和Ⅲ型AEG，Siewert Ⅱ型AEG的切除范围在欧美和东亚国家存在不同，全胃切除或食管切除孰优孰劣有待更多临床研究结果验证。未来AEG的诊断与治疗需要通过多学科协作的模式共同完成。
The incidence of adenocarcinoma of esophagogastric junction （AEG） is increasing worldwide during recent decades. Surgical resection still plays the most important role in comprehensive therapy for AEG. However, due to the specifics of tumor position and biological features, there are many controversies on surgical problems inlcuding preoperative clinical classification, surgical approaches, regional lymphadenectomy and resection extension. New TNM staging defines new staging for AEG, while traditional Siewert classification is still the key typing method to decide the surgical strategies. Compared with Siewert type I and type Ⅲ AEG, there are different resection extension for Siewert type Ⅱ AEG between western and eastern countries. Moreover, the comparison between total gastrectomy and esophageal resection for Siewert type Ⅱ AEG is needed to be evaluated further in more researches. The diagnosis and treatment of AEG in the near future will be completed through multidisciplinary team.
出处
《中华消化外科杂志》
CAS
CSCD
北大核心
2016年第11期1048-1051,共4页
Chinese Journal of Digestive Surgery
基金
教育部留学回国人员科研基金（20144908）
关键词
食管胃结合部肿瘤
腺癌
外科手术
Esophagogastric junction neoplasms,adenocarcinoma
Surgical procedures,operative
