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藿芪灌注液治疗奶牛卵巢静止和持久黄体临床试验

Treatment trials of inactive ovary and persistent corpus luteum in dairy cows by Huoqi perfusion
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摘要 为了评价藿芪灌注液治疗奶牛卵巢静止和持久黄体的临床效果,将确诊为患持久黄体和卵巢静止的病牛各40头随机分为4组,分别为藿芪灌注液高、中(推荐剂量)、低剂量治疗组和对照药物治疗组,每组10头。试验组每头牛每次分别按150 m L、100 m L和50 m L的剂量子宫灌注,隔日1次,4次为1个疗程;对照药物治疗组为促孕灌注液,每次100 m L,隔日1次,4次为1个疗程。试验结果表明,用藿芪灌注液治疗奶牛持久黄体的高、中、低剂量组的治愈率分别为80%、70%和50%,总有效率分别为90%、90%和60%;对照组治愈率80%,总有效率90%,藿芪灌注液高剂量组、中剂量组与对照组的治愈率和总有效率均显著高于低剂量组(P<0.05),高剂量组与中剂量组之间无显著性差异(P>0.05);高、中剂量组与对照组之间无显著性差异(P>0.05)。用藿芪灌注液治疗奶牛卵巢静止高、中、低剂量组的治愈率分别为90%、80%和60%,总有效率分别为100%、100%和70%;对照组治愈率80%,总有效率90%,高剂量组、中剂量组和对照组的治愈率和总有效率均显著高于低剂量组(P<0.05),高剂量组与中剂量组之间无显著性差异(P>0.05),高、中剂量组与对照组之间无显著性差异(P>0.05)。 To evaluate treatment effect of Huoqi perfusion on inactive ovary and persistent corpus luteum, forty dairy cows with persistent corpus luteum and ovarian quiescence were divided into four groups, which were respectively treated with high, medium(recommended dose), low dose of Huoqi perfusate, and control group were treated with Cuyun perfusion(n =10). The dosage of experimental groups was 150 m L, 100 m L and 50 m L at once every two days, four times for 1 course. The control group was given 100 m L once every two days, four times for 1 course. The results were follows: The cure rate of high, medium, low dose of Huoqi perfusion liquid and control medicine on persistent corpus luteum was 80%, 70%, 50% and 80% with total effective rate of 90%,90%, 60% and 90% respectively, Meanwhile the cure rate of high, medium, low dose of Huoqi perfusion liquid and control medicine on inactive ovary respectively was 90%, 80%, 60% and 80% with total efficiency of 100%, 100%, 70% and 90%.Statistic showed that for both inactive ovary and persistent corpus luteum, the cure rate and total effective rate of high, medium dose group and control group were significantly higher than that of low dose group(P〈0.05), while there were no significant difference among high dose, middle dose group and control group(P〈0.05).
作者 严作廷 王东升 张世栋 董书伟 苗小楼 那立冬 闫宝琪 朱新荣 韩积清 王雪郦 YAN Zuo-ting WANG Dong-sheng ZHANG Shi-dong DONG Shu-wei MIAO Xiao-lou NA Li- dong YAN Bao-qi ZHU Xin-rong HAN Ji-qing WANG Xue-li(Lanzhou Institute of Animal Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou Gansu 730050 Gansu Holstein Cow Breeding Center, Lanzhou Gansu 730080 Dairy Farm in Qinwangchuan of Gansu Province, Yongdeng Gansu 730000 Dairy Farm in Chengguan District of Lanzhou City, Lanzhou Gansu 730050, China)
出处 《中兽医医药杂志》 2016年第5期51-54,共4页 Journal of Traditional Chinese Veterinary Medicine
基金 "十二五"国家科技支撑计划项目(2012BAD12B03) 中国农业科学院农业科技创新工程(CAAS-ASTIP-2014-LIHPS-03) 中央级公益性科研院所基本科研业务费专项资金(1610322015003)
关键词 奶牛 持久黄体 卵巢静止 疗效 dairy cows persistent corpus luteum inactive ovary cure effect
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