摘要
目的:观察经皮穴位电刺激(TEAS)治疗对IVF肾气虚型患者冻胚移植周期子宫内膜容受性的影响。方法:将我院收集的153例符合纳入标准的行冻胚移植的肾气虚型患者随机分为TEAS治疗组、MOCK组、对照组。观察3组患者治疗前后临床指标的变化,以及妊娠结局的差异。结果:3组患者的平均年龄、不育年限、体重指数、基础FSH比较差异无统计学意义。治疗后,TEAS组患者中医证候评分较治疗前明显降低,差异有统计学意义(P<0.05)。黄体酮注射日TEAS组的子宫内膜厚度高于MOCK组和对照组,差异有统计学意义(P<0.05);TEAS组A型与AB型子宫内膜百分比、(+、++)型子宫内膜下血流明显高于MOCK组和对照组,差异有统计学意义(P<0.05);黄体酮注射日3组血清E2、P比较,差异无统计学意义(P>0.05);TEAS组PI、RI、S/D低于治疗前,与MOCK组、对照组比较明显降低,差异均有统计学意义(P<0.05),治疗前后MOCK组与对照组两组间、组内比较差异均无统计学差异(P>0.05)。TEAS组HCG阳性率及临床妊娠率明显高于MOCK组与对照组,差异有统计学意义(P<0.05)。MOCK组与对照组比较无统计学差异(P>0.05)。结论:TEAS治疗能改善IVF肾气虚型患者的中医临床症状及体征,增加子宫内膜厚度,降低子宫内膜血流参数PI、RI、S/D,进而提高患者的子宫内膜容受性,改善临床妊娠结局。
Objective：To observe the effect of TEAS therapy on endometrial receptivity of IVF patients with kidney Qi deficiency. Methods：Collect 153 patients met the inclusion criteria frozen embryo transplantation of kidney Qi deficiency patients were randomly divided into TEAS treatment group,MOCK group and control group. To observe the changes of clinical indicators of the three groups before and after treatment,and the difference of the outcome of pregnancy. Results：There was no significant difference in the mean age,sterile time,body mass index and basic FSH between the three groups. After treatment,the TCM syndrome score of TEAS group was significantly lower than before treatment,the difference was statistically significant（P〈0.05）. On the day of progesterone injections,TEAS group of endometrial thickness is higher than the MOCK group and control group,the difference was statistically significant（P〈0.05）;in TEAS group A and AB type endometrial percentage,（＋）（＋＋）type of endometrial blood flow was significantly higher than that of the MOCK group and control group,the difference was statistically significant（P〈0.05）;three groups of serum E2,P level,the difference was not statistically significant（P〉0.05）;After treatment group the PI,RI and S/D of the TEAS group are decreased significantly,and lower than MOCK group and the control group,the differences were statistically significant（P〈0.05）;before and after treatment MOCK group and control group,differences were not statistically significant（P〉0.05）. The positive rate and clinical pregnancy rate of TEAS group was significantly higher than that in MOCK group and control group,the difference was statistically significant（P〈0.05）. There was no significant difference between the MOCK group and the control group（P〉0.05）. Conclusion：TEAS treatment can improve IVF kidney Qi deficiency patients of clinical symptoms and signs,increase the thickness of the endometrium and reduce endometrial blood flow parameters
出处
《辽宁中医药大学学报》
CAS
2016年第10期188-191,共4页
Journal of Liaoning University of Traditional Chinese Medicine
关键词
经皮穴位电刺激
体外受精胚胎移植
肾气虚
子宫内膜容受性
transcutaneous electrical acupoint stimulation
IVF-ET
kidney Qi deficiency
endometrial receptivity
