摘要
目的探讨体重指数(BMI)对食管癌根治术的根治效果及手术风险的影响。方法回顾性分析2014年3月至2015年3月四川大学华西医院胸外科行食管癌根治术494例患者的临床资料,其中男296例、女98例,年龄60(36~81)岁。根据BMI将患者分为三组:肥胖组(BMI≥25 kg/m^2),74例;正常体重组(18.5 kg/m^2≤BMI<25 kg/m^2),345例;低体重组(BMI<18.5 kg/m^2),75例。结果低体重组、正常体重组和正常体重组术中出血量[(213.33±55.10)ml vs.(218.90±60.76)ml vs.(217.30±61.10)ml]、手术时间[(197.07±52.47)min vs.(208.35±96.84)min vs.(182.84±63.06)min]、术后总并发症发生率[38.7%(29/75)vs.43.2%(149/345)vs.39.2%(29/74)]、淋巴结清扫数(916.18±6.64 vs.16.68±8.48 vs.17.07±8.26)和转移淋巴结清扫数目(1.42±2.53 vs.1.32±2.51 vs.2.45±4.08)的差异均无统计学意义。结论肥胖和低体重不会增加食管癌患者手术风险或影响手术根治效果,故肥胖和低体重不应影响食管癌患者对手术治疗的选择。
Objective To explore the effect of body mass index （BMI） on therapeutic effect and surgical risk of esophagectomy. Methods We retrospectively collected the data of 494 patients who underwent esophagectomy in West China Hospital of Sichuan University between March 2014 and March 2015. According to BMI, all patients were allocated to three groups： an obesity group （BMI t〉 25 kg/m2） of 74 patients, a normal weight group （18.5 kg/m2≤ BMI〈25 kg/m2） of 345 patients, and a low weight group （BMI〈 18.5 kg/m2） of 75 patients. Results There were no statistical differences in the intraoperative blood loss （213.33±55.10 ml vs. 218.90±60.76 ml vs. 217.30±61.10 ml）, operation time （197.07±52.47 min vs. 208.35±96.84 min vs. 182.84±63.06 min）, incidence of postoperative complication （38.7% （29/75） vs. 43.2% （149/345） vs. 39.2% （29/74）, the number of resected lymphnodes （116.18±6.64 vs. 16.68 ±8.48 vs. 8.48±8.26）, and the number of the metastatic lymphnodes （1.42±2.53 vs. 1.32±2.51 vs. 2.45±4.08） among the low weight group, the normal weight group, and the obesity group. Conclusion Obesity and low weight do not increase the surgical risk and influence the surgical outcome. Therefore, obesity and low weight should not interfere with the operative choice of patients with esophageal cancer.
出处
《中国胸心血管外科临床杂志》
CAS
CSCD
2016年第11期1039-1043,共5页
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
关键词
食管肿瘤
体重指数
外科手术
Esophageal cancer
Body mass index
Surgery
