摘要
目的:探讨保留盆腔自主神经的根治性子宫切除术( NSRH)对术后肛门直肠功能的长期影响。方法以符合条件的56例宫颈癌患者为研究对象,应用数字表随机分为根治性子宫切除术( RH)组和NSRH组。比较术后1年的排便功能和肛门直肠测压结果。结果两组各剔除2例,纳入随访各26例。与RH组相比,NSRH组的便秘和慢性腹泻发生率均显著降低[2例(7.7%)、8例(30.8%),1例(3.8%)、6例(23.1%)],差异均有统计学意义(χ2值分别为4.457、4.127,P均<0.05),NSRH组和RH组与术前比较排便功能自我评价无明显改变、较差、很差分别为10例(38.5%)、5例(19.2%),7例(26.9%)、3例(11.5%),9例(34.6%)、18例(69.2%),差异有统计学意义(χ2=6.267,P=0.044),NSRH组与RH组比较,肛管最大缩榨压较高[(132.7±43.6)、(119.5±45.3) mmHg],初始感觉阈值和初始排便阈值较低[(38.6±10.5)、(45.8±12.4) mmHg,(78.3±33.2)、(90.6±40.9) mmHg],差异均有统计学意义( t值分别为2.116、2.326、2.208,P均<0.05]。结论 RH会导致更为严重的长期肛门直肠功能紊乱,NSRH更有助于保护排便功能。
Objective To investigate the long-term effect of nerve-spring radical hysterectomy( NSRH) on anorectal function after radical hysterectomy. Methods Fifty-six cases of uterine cervical carcinoma patients who met the criteria were selected for the study and were randomly divided into RH group and NSRH group. Defecation functional and anorectal manometry were compared at 1 year after surgery. Results There were 2 patients were excluded both in the two groups, and 26 cases were included in the follow up of each group. Compared with RH group, NSRH group had a lower constipation and chronic diarrhea incidence ( 2 (7. 7%),8(30. 8%);1(3. 8%),6(23. 1%);χ2=4. 457,4. 127P〈0. 05),a better self-evaluation bowel func-tion(no significant change:10(38. 5%),5(19. 2%);poor:7(26. 9%),3(11. 5%);very poor:9(34. 6%),18 (69. 2%);χ2=6. 267,P=0. 044;P〈0. 05),a higher level of maximal anal squeeze pressure((132. 7±43. 6) mmHg,(119. 5±45. 3) mmHg;t=2. 116,P〈0. 05),a lower level of threshold perception of distension((38. 6 ±10. 5) mmHg,(45. 8±12. 4) mmHg;t=2. 326,P〈0. 05) and threshold perception of evacuative stimulus ((78. 3±33. 2) mmHg,(90. 6±40. 9) mmHg;t=2. 208,P〈0. 05). Conclusion RH may cause more serious long-term anorectal dysfunction,while NSRH help to protect defecation function.
出处
《中国综合临床》
2016年第9期833-836,共4页
Clinical Medicine of China
关键词
宫颈癌
盆腔自主神经
根治性子宫切除术
肛门直肠功能
Uterine cervical carcinoma
Pelvic autonomic nerve
Radical hysterectomy
Anorec-tal function