摘要
目前肾小球肾炎分类和病理报告模式缺乏标准化,疾病诊断之间的层次关系缺乏统一性。2015年2月肾脏病理学家和肾病学家在美国梅奥医学中心举行会议,提出了基于病因学和发病机制将肾小球肾炎分为五类,并制定出标准化、统一的描述性语言和层次分明的疾病诊断体系,最终达成了"梅奥诊所及肾脏病理学会关于肾小球肾炎病理分类、诊断及报告的共识"。共识将增生性肾小球肾炎根据病因和发病机制分为5类:免疫复合物相关性肾小球肾炎、寡免疫复合物性肾小球肾炎、抗肾小球基底膜肾炎、单克隆免疫球蛋白相关性肾小球肾炎和C3肾病。共识提出病理诊断应包括主要诊断和次要诊断,主要诊断应包含病种(或损伤的类型)、病种的评分和(或)分级和(或)分类,次要诊断单独列出,包含其他合并存在的、不足以导致主要诊断的病变。共识最后对光镜、免疫荧光、电镜和其他辅助诊断手段的报告模式进行了规范。
At present, there is a lack of standardization in the classification of glomerular nephritis and pathological report, and the lack of unity between the levels of the disease diagnosis. A group of renal pathologists and nephrologists met at the Mayo Clinic （Rochester, MN） on February 20, 2015 to reach a consensus on an etiology/pathogenesis-based classification and standardize reporting of GN,, finally achieved the ＂Mayo Clinic/renal pathology society glomerulonephritis pathological classification, diagnosis and report on the consensus＂. In this consensus, glomerulonephritis （GN） is classified into the following five etiology/pathogenesis-based types, each with specific disease entities： immune-complex GN, pauci-immune GN, antiglomerular basement membrane GN, monoclonal Ig GN and C3 glomernlopathy. A pattern diagnosis should be reported as primary diagnosis and secondary diagnosis. Primary diagnosis should include the primary disease （or primary injury type）, score/grade/class for disease entities. Secondary diagnosis should be reported separately and include coexisting lesions that do not cause the primary diagnosis. Guidelines for the report format, light microscop）5 microscopy, electron microscopy, and ancillary studies are also provided in current consensus.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2016年第10期870-873,共4页
Chinese Journal of Practical Internal Medicine
关键词
梅奥诊所
肾小球肾炎
病理分类
病理诊断
Mayo Clinic
glomerulonephritis
pathological classification
pathological diagnosis
