摘要
慢性萎缩性胃炎癌前病变(Precancerous lesions of gastric cancer,PLGC)属于中医"胃痞"范畴。其病因多为毒浊内蕴于心下,毒瘀互结是其基本病机,正气亏虚是慢性萎缩性胃炎癌前病变的病理基础,关键病理因素可概括为毒、瘀、虚。其发病以正虚为本,以毒、瘀为标。在病变过程中,机体正气亏虚是内因,感受浊毒邪气是外因,浊毒内蕴、毒瘀互结则是其主要病理变化,也是造成慢性萎缩性胃炎癌前病变高患病率和发病率的关键。治当以解毒化瘀扶正为法,辨证论治,提高疗效,降低转癌率。
PLGC（precancerous lesions of gastric cancer） of chronic atrophic gastritis belongs to Weipi in TCM. Its etiology is turbid retention in stomach and the basic pathogenesis is the tangling of toxin and bold stasis and the pathological basis is deficiency of health energy. The key pathogenesis can be summed up into toxin, blood stasis and deficiency. Its onset is because of deficiency of healthy energy and toxin and blood stasis in appearance. During the disease develo- ping process, the internal cause is deficiency of healthy energy in body and external cause turbid attacking. The main pathological changes are internal accumulation of turbid evil and toxin and bold stasis tangling,which are the key to leading the high prevalence and incidence of PLGC. We have to resolve the toxin, dissolve blood stasis and strengthen body resistance actively according to syndrome differentiation in order to improve the curative effect and to reduce the gastric carcinoma conversion rate.
出处
《中华中医药学刊》
CAS
北大核心
2016年第10期2390-2392,共3页
Chinese Archives of Traditional Chinese Medicine
基金
国家自然科学基金项目(30973826)
国家重大新药创制科技重大专项项目(2009ZX09502-015)
山东省中医药科技发展计划项目(2013zdzk-016)
关键词
慢性萎缩性胃炎
胃癌前病变
毒瘀互结
正气亏虚
病因病机
chronic atrophic gastritis
PLGC
tangling of toxins and blood stasis
deficiency of healthy energy
etiology and pathogenesis
