期刊文献+

妊娠合并自身免疫性肝炎对母胎的影响及诊治

Diagnosis and treatment of autoimmune hepatitis complicating pregnancy and its influence on mothers and fetuses
原文传递
导出
摘要 妊娠期间大部分自身免疫性肝炎(AIH)患者可以维持病情稳定甚至缓解,但分娩后容易出现复发,严重者可出现肝纤维化、甚至肝硬化、肝昏迷。AIH患者发生妊娠不良事件的概率增加,如早产、流产等。AIH患者妊娠期间遵循肝病医生的医嘱将泼尼松减至最小剂量继续维持治疗。妊娠的AIH患者需要在产科和肝病医生的共同监护下,在妊娠期及产后密切随访。 During pregnancy, most of autoimmune hepatitis(AIH) patients can maintain stable or even be relieved, but they are prone to have recurrence after delivery,and some of them may develop liver fibrosis,liver cirrhosis, and even hepatic coma.The occurrence rate of adverse pregnancy outcomes in AIH patients increased, such as premature birth, abortion and so on.AIH patients during pregnancy should continue to maintain prednisone treatment at a minimum dose according to the doctor's guidance. AIH patients at pregnancy need to be closely followed up during pregnancy and postpartum by the obstetricians and hepatologists.
作者 范玲 周莉
出处 《中国实用妇科与产科杂志》 CAS CSCD 北大核心 2016年第10期963-966,共4页 Chinese Journal of Practical Gynecology and Obstetrics
关键词 妊娠 自身免疫性肝炎 诊断 治疗 pregnancy autoimmune hepatitis diagnosis treatment
  • 相关文献

参考文献2

二级参考文献64

  • 1Krawitt EL. Autoimmune hepatitis[J]. N Engl J Med, 2006, 354(1): 54-66. 被引量:1
  • 2Yang F, Wang Q, Bian Z, et al. Autoimmune hepatitis: east meets west[J]. J Gastroenterol Hepatol, 2015, 30(8): 1230-1236. DOI: 10.1111/jgh.12952. 被引量:1
  • 3Liberal R, Grant CR, Mieli-Vergani G, et al. Autoimmune hepatitis: a comprehensive review[J]. J Autoimmun, 2013, 41: 126-139. DOI: 10.1016/j.jaut.2012.11.002. 被引量:1
  • 4Gronbek L, Vilstrup H, Jepsen P. Autoimmune hepatitis in Denmark: incidence, prevalence, prognosis, and causes of death. A nationwide registry-based cohort study[J]. J Hepatol, 2014, 60(3): 612-617. DOI: 10.1016/j.jhep.2013.10.020. 被引量:1
  • 5Czaja AJ, Manns MP. Advances in the diagnosis, pathogenesis, and management of autoimmune hepatitis[J]. Gastroenterology, 2010, 139(1): 58-72, e4. DOI: 10.1053/j.gastro.2010.04.053. 被引量:1
  • 6Lohse AW, Mieli-Vergani G. Autoimmune hepatitis[J]. J Hepatol, 2011, 55(1): 171-182. DOI: 10.1016/j.jhep.2010.12.012. 被引量:1
  • 7Okazaki K, Uchida K, Koyabu M, et al. IgG4 cholangiopathy: current concept, diagnosis, and pathogenesis[J]. J Hepatol, 2014, 61(3): 690-695. DOI: 10.1016/j.jhep.2014.04.016. 被引量:1
  • 8Vergani D, Alvarez F, Bianchi FB, et al. Liver autoimmune serology: a consensus statement from the committee for autoimmune serology of the International Autoimmune Hepatitis Group[J]. J Hepatol, 2004, 41(4): 677-683. 被引量:1
  • 9Couto CA, Bittencourt PL, Porta G, et al. Antismooth muscle and antiactin antibodies are indirect markers of histological and biochemical activity of autoimmune hepatitis[J]. Hepatology, 2014, 59(2): 592-600. DOI: 10.1002/hep.26666. 被引量:1
  • 10Czaja AJ, Shums Z, Norman GL. Frequency and significance of antibodies to soluble liver antigen/liver pancreas in variant autoimmune hepatitis[J]. Autoimmunity, 2002, 35(8): 475-483. 被引量:1

共引文献90

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部