摘要
目的探讨五味消毒饮与黄芪建中汤配合西药治疗幽门螺杆菌感染的胃溃疡患者临床疗效,为提高患者治疗的安全性及有效性提供理论依据。方法选取2013年2月-2015年2月在医院接受治疗122例幽门螺杆菌感染胃溃疡患者进行研究,并将其随机平均分为观察组与对照组,各61例,对照组患者采用西药治疗方法进行治疗,观察组在对照组的基础上加用五味消毒饮与黄芪建中汤进行治疗;比较两组患者幽门螺杆菌转阴率,复发率和不良反应发生率,并对两组患者治疗效果进行比较。结果幽门螺杆菌转阴率观察组为91.80%,对照组为70.49%,差异有统计学意义（χ^2=9.741,P〈0.05）;复发及不良反应发生率观察组均显著低于对照组,差异有统计学意义（P〈0.05）;治疗总有效率观察组为96.72%,对照组为72.13%,观察组明显优于对照组,差异有统计学意义（χ^2=8.201,P〈0.05）。结论五味消毒饮与黄芪建中汤配合西药治疗幽门螺杆菌感染胃溃疡患者的临床疗效显著,阴转率明显提高,复发及不良反应发生率低,治愈率和安全性均全面提高,临床应用中值得推广。
OBJECTIVE To investigate clinical efficacy of Wuweixiaoduyin and Huangqijianzhong soup with gastric ulcer medicine in treatment of Helicobacter pylori infection,so as to provide a theoretical basis for improving the safety and effectiveness of patient care.METHODS A total of 122 cases of gastric ulcer patients with H.pylori infection from Feb.2013 to Feb.2015 in the hospital were selected as study objects,and were randomly divided into observation group and control group,with 61 cases in each group.Patients in control group were treated with western medicine methods of treatment,and in observation group were treated with Wuweixiaoduyin and Huangqijianzhong soup based on control group.Helicobacter pylori negative rate compared to the situation of the two groups of patients were compared.The negative conversion rates,recurrence rates and adverse reactions rates of H.pylori of the two groups were compared,and the treatment situation were also compared.RESULTS The H.pylori negative rates of control group and observation group were 91.80% and 70.49%,with significant difference（χ^2=9.741,P〈0.05）.The recurrence rate and adverse reactions rate of observation group were significantly lower than those of control group（χ^2=3.861,P〈0.05）.The total effective rate of observation group was96.72%,which was significantly higher than 72.13% of control group（χ^2=8.201,P〈0.05）.CONCLUSION Wuweixiaoduyin and Huangqijianzhong soup combined with western medicine have clinical efficacy in patients with gastric ulcer,and can significantly improve negative rate of H.pyloriinfection,reduce the recurrence rate and adverse reactions rate,and improve the cure rate and safety,and clinical application should be promoted.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2016年第19期4376-4378,共3页
Chinese Journal of Nosocomiology
基金
河南省卫生厅科技攻关基金资助项目(072103810502)
关键词
幽门螺杆菌
感染
胃溃疡患者
五味消毒饮
黄芪建中汤
西药治疗
Helicobacter pylori
Infection
Gastric ulcer
Wuweixiaoduyin
Huangqijianzhong soup
Western medicine
