摘要
目的:探讨文拉法辛治疗老年精神疾病症状的疗效及其影响因素。方法:选取我院老年精神疾病患者80例,均给予文拉法辛并评定疗效,根据结果分为有效及无效组。收集两组治疗后的HAMD、ATQ、BPRS等临床资料,并比较两组在这些方面的差异。结果:两组患者在HAMD迟滞因子分、ATQ总分、BPRS焦虑抑郁因子、阳性精神病家族史、伴有焦虑症状、一年内未接受治疗和总病程等方面存在差异,差异具有统计学意义(P<0.05)。Logistic回归分析表明伴有焦虑症状和一年内未接受治疗对疗效有影响。结论:文拉法辛对于老年精神疾病症状有很好的疗效,同时控制患者的焦虑情绪和及时接受治疗能够提高文拉法辛治疗老年精神疾病症状的疗效。
Objective ： To explore the curative effect of venlafaxine on elderly psychiatric symptoms and its influence factors. Methods： 80 patients with elderly psychiatric symptoms admitted in our hospital were se- lected. All patients were treated with single venlafaxine. Evaluated the curative effect before and after treat- ment, through the results who were divided into effective and ineffective group. And collected and compared clinical data of HAMD, ATQ, BPRS. the two groups in patients after treatment.. Results： Before and after treatment, HAMD scores and deducted rate had obvious changes （P〈0.05） ;Two groups of patients had differ- ences in HAMD retardation factor points, ATQ total score, BPRS anxiety depression factor points, positive family history of mental illness the anxiety symptoms, untreated and total duration within a year （P〈0.05）. Logistic regression analysis showed that the anxiety symptoms within one year and untreated had significant in- fluence on the curative effect. Conclusion： Venlafaxine for elderly psychiatric symptoms have good curative effect, and at the same time the controlling of the patient＇s anxiety and timely treatment can improve the ven- lafaxine curative effect on elderly psychiatric symptoms.
出处
《河北医学》
CAS
2016年第9期1414-1416,共3页
Hebei Medicine
基金
国家科技重点专项课题
(编号:2012ZX10002015)
关键词
文拉法辛
精神疾病
影响因素
Venlafaxine
Psychiatric symptoms
Influence factors
