摘要
目的探讨胎儿先天畸形的病因、发病率、分类及其致畸高危因素,为采取有效干预措施提供理论依据。方法回顾性分析于我院接受产前超声检查的31 500胎的资料,重点分析其中1 467胎确诊为畸形胎儿的临床资料及致畸高危因素。结果检查胎儿31 500胎,其中1 467胎诊断为先天性畸形（共1 787处畸形）。胎儿畸形的发生率为4.66%（1467/31 500）;孕妇年龄〈20岁或≥35岁胎儿畸形发生率均高于年龄20~〈35岁的孕妇（P均〈0.05）;畸形胎儿孕妇的平均年龄高于正常胎儿孕妇（P〈0.05）;胎儿最常见的畸形为心脏及骨骼畸形（构成比分别为20.76%、9.84%）;孕期感冒发热、服药、高危工作是导致胎儿畸形的主要危险因素。结论加强孕妇的孕前和孕期保健,高危人群按规定做好产前检查,及早发现胎儿畸形,提前终止严重畸形胎儿的妊娠,能达到优生的目的。
Objective To investigate the etiology,incidence,classification and teratogenic risk factors of fetal malformation,and provide a theoretical basis for effective intervention.Methods Clinical data of 1 467 fetuses with malformations in our hospital were collected,and fetal malformations and teratogenic risk factors were analyzed retrospectively.ResultsTotally 31 500 fetuses were examined,and 1 467 fetuses were diagnosed fetal congenital malformations（1 787 fetal malformation in total）.The incidence of fetal malformation was 4.66%（1 467/31 500）.Malformation incidence of age 20 years or≥35 years old of pregnant women were higher than the pregnant women aged 20—35 years（both P0.05）.The average age of pregnant women of infant deformity was higher than pregnant women of normal fetuses（P0.05）.The most common abnormality were heart and skeletal deformities（constituent ratio respectively was 20.76% and 9.84%）.Early pregnancy colds,fever,medication,high-risk work were the major risk factor for fetal malformations.Conclusion Strengthen preconception and prenatal care for pregnant women,early detection of fetal malformations,early termination of severe fetal deformity pregnancy,can improve the quality of the birth of the fetus.
出处
《中国介入影像与治疗学》
CSCD
北大核心
2016年第10期632-635,共4页
Chinese Journal of Interventional Imaging and Therapy
关键词
胎儿
畸形
危险因素
干预措施
Fetus
Abnormalities
Risk factors
Intervention
