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孕中期孕妇血D-二聚体检测对早发型重度子痫前期预测价值的研究 被引量:6

The value of prediction study on early-onset severe pre-eclampsia by maternal serum D-dimer in second-trimester pregnancy
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摘要 目的研究孕中期孕妇血D-二聚体水平检测对早发型重度子痫前期的预测价值。方法选择2014年1月-2015年12月在我院门诊早孕期建卡的单胎妊娠无合并症的孕妇300例作为研究对象,孕周为13-27周+6d,用酶联免疫吸附(ELESA)法进行血清D-二聚体水平检测。共有107例孕妇完成研究,规律产检并在我院分娩。实验分组:A组血清D-二聚体水平高于3.5mg/ml,B组血清D-二聚体水平不高于3.5mg/ml。结果早发型重度子痫前期发病率A组高于B组,有统计学差异,P<0.05。结论孕中期血清D-二聚体水平检测对早发型重度子痫前期发病有较好的预测价值。 Objective To study the value of prediction on early-onset severe pre-eclampsia by maternal serum D-Dimer in second-trimester pregnancy. Methods 300 pregnancy women with gestational age 13-27 weeks+6 days and without any complications in our hospital outpatient department form January 2015 to December 2015 were involved. The levels of serum D-Dimer were measured by ELASA. Only 107 women went through the whole study. They were divided into 2 groups,Group A included patients with serum D-Dimer 3.5mg/ml,and Group B included patients with serum D-Dimer ≤3.5mg/ml. Results The occurrence rate of early-onset severe pre-elampsia in group A was significantly higher than group B,P〈0.05. Conclusion The level of serum D-Dimer in second-trimester pregnancy could have better predictive value for early-onset severe pre-elampisa.
作者 熊贤海 郑丹 XIONG Xianhai ZHENG Dan.(Department of Gynecology and Obstetrics ,the Third Affiliated Hospital of Nanchang U- niversity and the Firs t Hospital of Nanchang, Nanchang, Jiangxi, 330008, China)
出处 《江西医药》 CAS 2016年第9期884-886,共3页 Jiangxi Medical Journal
关键词 D-二聚体 早发型重度子痫前期 预测价值 D-Dimer Early-onset severe pre-eclampsia Predictive value
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