摘要
目的探讨急诊治疗严重哮喘合并呼吸衰竭的方法及其效果。方法选取2012年1月~2015年12月100例严重哮喘合并呼吸衰竭患者作为研究对象,采取随机数字表法将其分为对照组与观察组,各50例。对照组实施常规对症治疗,观察组在常规对症治疗的同时实施无创正压通气治疗。比较两组患者治疗前后的二氧化碳分压（Pa CO_2）、氧分压（Pa O_2）、p H值、呼吸频率（RR）,并对比两组患者的住院时间、死亡情况。结果治疗后,两组患者Pa CO_2、RR均明显下降（P〈0.05）,Pa O_2、p H值均明显增高（P〈0.05）,且两组患者各项指标进行比较,差异有统计学意义（P〈0.05）。与对照组比较,观察组住院时间明显缩短（P〈0.05）。观察组中无死亡病例,对照组死亡率为4%,差异无统计学意义（P〉0.05）。结论在严重哮喘合并呼吸衰竭患者的急诊治疗中,实施无创正压通气可有效改善患者的血氧状况,纠正缺氧及酸中毒状态,有利于降低患者的死亡率。
Objective To explore the emergency treatment of severe asthma with respiratory failure and its effect.Methods From January 2012 to December 2015,100 cases of patients with severe asthma and respiratory failure were selected as the subjects of this study.The patients were randomly divided into the control group and the observation group by taking the digital random table method,50 cases in each group.The control group was given routine treatment,the observation group was treated with noninvasive positive pressure ventilation at the same time.The carbon dioxide partial pressure（Pa CO_2）,oxygen partial pressure（Pa O_2）,p H value,respiratory rate（RR） before and after treatment were compared between two groups,and the time of hospital stay and death were compared between two groups.Results After treatment,Pa CO_2 and RR in two groups were significantly decreased（P0.05）,Pa O_2,p H value in two groups were significantly increased（P0.05）,and the indexes were compared between two groups,with the statisticant differences（P0.05）.Compared with the control group,the time of hospital stay in the observation group was significantly shorter（ P0.05）.There were no deaths in the observation group,the rate of death in the control group was 4%,the difference was not statistically significant（P0.05）.Conclusion In the emergency treatment of patients with severe asthma and respiratory failure,the implementation of noninvasive positive pressure ventilation can effectively improve the patient′s blood oxygen condition,correct the hypoxia and acidosis state,it is help to reduce the patient′s mortality.
出处
《中国当代医药》
2016年第26期25-27,共3页
China Modern Medicine
关键词
严重哮喘
呼吸衰竭
急诊
无创正压通气
Severe asthma
Respiratory failure
Emergency
Noninvasive positive pressure ventilation
