摘要
吸入一氧化氮(inhaled nitrous oxide,iNO)能降低儿童急性呼吸窘迫综合征(pediatric acute respiratory distres ssyndrome,PARDS)的肺动脉压力,改善通气/血流匹配,从而增加动脉血氧合,但该作用持续时间短。从现有研究来看,iNO不能改善患者预后。目前不推荐在儿童ARDS治疗中常规使用iNO。然而,对存在肺动脉高压或严重右心室衰竭的儿童ARDS可以考虑进行iNO治疗。此外,iNO可作为严重儿童ARDS的急救性治疗措施,为进行其他治疗赢得时间。
Inhaled nitrous oxide (iNO) can alleviate pulmonary hypertension and enhance ventilation -peffusion matching to improve oxygenation in pediatric acute respiratory distress syndrome (PARDS). But duration of improvement was short. From the existing researches ,iNO can't effectively improve outcome in PARDS. So iNO is not recommended for routine use in PARDS. However, iNO may be used in patients with documented pulmonary hypertension or severe fight ventricular dysfunction. In addition, iNO can be a rescue intervention for severely PARDS to buy time and allow other therapies.
出处
《中华实用儿科临床杂志》
CSCD
北大核心
2016年第18期1390-1393,共4页
Chinese Journal of Applied Clinical Pediatrics
关键词
吸入一氧化氮
急性呼吸窘迫综合征
儿童
Inhaled nitrous oxide
Acute respiratory distress syndrome
Child