摘要
目的探讨PLF联合榄香烯注射液治疗恶性胸腔积液的疗效。方法选取我科2011年3月至2016年3月收治的恶性胸腔积液52例为研究对象,随机分为I组(榄香烯注射液+顺铂+亚叶酸钙+氟脲嘧啶)和II组(顺铂+亚叶酸钙+氟脲嘧啶)各26例,比较两组疗效、KPS评分、不良反应发生情况。结果治疗4周后,I组有效率为84.6%,显著高于II组的57.7%(P<0.05);I组KPS评分为(78.7±3.2)分,显著高于II组的(71.5±4.1)分(P<0.05);I组不良反应发生率为30.8%,II组不良反应发生率为34.6%,组间比较差异无统计学意义(P>0.05)。结论榄香烯联合PLF治疗恶性胸腔积液安全有效,可在临床广泛应用。
Objective To investigate the effect of PLF combining elemene on malignant pleural effusion. Methods Fifty- two cases of patients with MPE were selected and divided into I group （26 cases, elemene＋PLF） and II group （26 cases, PLF）, the curative effect between two groups were compared between two groups. Results The effective rate （84.6%） and KPS score （78.7±3.2） were significantly better in I group than II group of 57.7% and 71.5±4.1 respectively （P〈O.05）, but the adverse reaction rate had no significant difference between I group with 30.8% and II group with 34.6% （P〉0.05）. Conclusion PLF combining elemene has a safety and great effect on MPE.
出处
《临床医学研究与实践》
2016年第19期51-52,共2页
Clinical Research and Practice
