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新一代测序在中枢神经系统感染病原体检测中的应用 被引量:14

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摘要 中枢神经系统(CNS)感染是神经科的一类常见疾病,由于临床实验室检测手段的限制,超过一半的CNS感染病例最终都无法明确诊断.目前临床应用最广泛的CNS感染病原体检测方法主要包括:脑脊液病原体形态学鉴定、外周血或脑脊液培养、脑脊液和血清的病原体抗体检测以及脑脊液的基因检测.各种方法均有其局限性,其中培养和病原体抗体检测的适用范围有限,对病毒而言尤为如此.
出处 《中华神经科杂志》 CAS CSCD 北大核心 2016年第9期737-740,共4页 Chinese Journal of Neurology
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