摘要
目的分析新生儿长期发热病因,以期为早期诊断及早期治疗提供临床依据。方法选择2004年1月至2013年12月本院新生儿中心住院,且符合新生儿长期发热纳入标准,对患儿一般情况及病因进行回顾性分析。结果共纳入患儿238例,男165例,女73例。其中肺炎196例、皮肤黏膜感染67例、败血症46例、脑膜炎/脑炎25例、新生儿坏死性小肠结肠炎24例是最常见病因,尿崩症4例是唯一非感染病因。脑膜炎/脑炎、败血症、尿崩症、免疫缺陷病及泌尿系感染患儿更易出现高热（P〈0.05）。肺炎患儿热型更易呈稽留热型或其他特殊热型（χ~2=4.581,P=0.032）。晚期出现长期发热新生儿更易罹患败血症、感染性腹泻、脑膜炎/脑炎等疾病（P〈0.05）。结论感染性疾病是新生儿长期发热最主要病因,尿崩症是唯一非感染因素。
Objective To study the etiologies of long duration fever in neonates and to provide clinical evidence for early diagnosis and intervention. Methods From January 1st, 2004 to December 31st, 2013, data from neonates admitted to the Department of Neonatology, Childrenˊs Hospital of Chongqing Medical University were retrospectively analyzed. Results Among 238 neonates with long duration fever, 165 cases were male and 73 female. Pneumonia（n = 196）, skin / mucosa infection （n =67）, sepsis （n = 46）, meningitis/ encephalitis （n = 25） and neonatal necrotizing enterocolitis （n = 24） were the most common etiologies. Diabetes insipidus was the only noninfectious cause of fever in this study. The incidence of high fever in cases diagnosed with meningitis/ encephalitis, sepsis, diabetes insipidus, immunodeficiency or urinary tract infection were significantly higher than other causes （P 〈0. 05） . Continuous fever or other special fever types were more common in cases diagnosed with pneumonia （ χ2 = 4. 581, P = 0. 032 ） . Incidences of sepsis, infectious diarrhea or meningitis/encephalitis in late neonates were significantly higher than early neonates （ P 〈 0. 05 ） . Conclusions Long duration fever in neonates is most likely caused by infectious diseases and diabetes insipidus is the only noninfectious cause of neonatal fever in our study.
出处
《中国新生儿科杂志》
CAS
2016年第5期335-338,共4页
Chinese Journal of Neonatology
关键词
发热
尿崩症
婴儿
新生
病因
Fever
Diabetes insipidus
Infant,newborn
Etiology
