摘要
通过PubMed、MEDLINE、美国Biological Abstracts、荷兰EMBASECNKI、中国生物医学文献数据库、中国学术期刊全文数据库、万方、维普等数据库对近10年针灸治疗化疗所致周围神经病变(CIPN)的相关文献进行检索,从实验设计、治疗方法、疗效评价、机制研究等方面对其概况进行综合分析和评述。结果显示针灸治疗可能具有一定的疗效,然而对其研究仍处于初级阶段,相关文献较少且质量相对不高,对针灸治疗CIPN的有效性仍存争议,需要高质量、大样本、多中心的随机对照试验及系统评价来证实其有效性,同时对于针灸治疗CIPN的作用机制也未完全明了,有待进一步研究和探索。
Literatures on acupuncture-moxibustion treatment of chemotherapy-induced peripheral neuropathy（CIPN） in the recent decade were searched in the databases of Pubmed, MEDLINE, Biological Abstracts, EMBASE, Sinomed, CNKI, Wanfang, VIP, et al. The general situation was comprehensively analyzed and reviewed from experimental design, treatment method, efficacy evaluation, mechanism research and so on. The results showed that acupuncture has a certain therapeutic effect, but the research is still in the preliminary stage, the relative literatures are insufficient and in a low quality. There is still a controversy on the efficacy of acupuncture in the treatment of CIPN. High quality, large sample and multicenter randomized controlled trials and systematic reviews are needed to verify the efficacy of acupuncture. The mechanism of acupuncture treatment of CIPN is still unclear and needs further research and exploration.
出处
《上海针灸杂志》
2016年第9期1025-1029,共5页
Shanghai Journal of Acupuncture and Moxibustion
基金
国家重点基础研究发展计划(2014CB543201)
中国临床肿瘤学科学基金资助项目(Y-L2014-004)
关键词
针灸疗法
周围神经病变
化疗
文献研究
药物相关的副作用及不良反应
Acupuncture-moxibustion
Peripheral neuropathy
Chemotherapy-induced
Literature research
Drug-related side effects and adverse reactions
