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右美托咪定联合七氟烷用于结直肠癌手术麻醉效果观察

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摘要 目的:观察右美托咪定(DEX)联合七氟烷用于结直肠癌手术的麻醉效果。方法:选择结直肠癌手术60例,随机分为观察组和对照组各30例。两组术中均采用七氟烷吸入麻醉;观察组术中给予DEX泵注,对照组给予等量生理盐水泵注。比较两组手术开始(t_0)、开始后15min(t_1)、30min(t_2)、60min(t_3)时吸入七氟烷的最低肺泡有效浓度(MAC)值、双频指数(BIS)、平均血压(MAP)、心率(HR)、术后睁眼时间、拔管时间及术后躁动评分等。结果:观察组t_0-t_3时的HR和MAC值显著低于对照组同时间节点(P<0.05);MAP和BIS值两组比较,差异不显著(P>0.05)。观察组睁眼时间、拔管时间和躁动评分分值均显著早(低)于对照组(P<0.05)。结论:DEX联合七氟烷用于结直肠癌手术麻醉效果优于单用七氟烷。
机构地区 解放军第
出处 《人民军医》 2016年第10期1026-1027,1029,共3页 People's Military Surgeon
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